Descriptive Analysis of Transient-State Observations for Thioredoxin/Glutathione Reductase (Sec597Cys) from Schistosoma mansoni.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemistry"
DOI: 10.1021/acs.biochem.3c00051
Abstract: Thioredoxin/glutathione reductase from Schistosoma mansoni (SmTGR) catalyzes the reduction of both oxidized thioredoxin and glutathione with electrons from reduced nicotinamide adenine dinucleotide phosphate (NADPH). SmTGR is a drug target for the treatment of Schistosomiasis, an… read more here.
Keywords: schistosoma mansoni; glutathione reductase; thioredoxin glutathione;
Potent Inhibitors of Thioredoxin Glutathione Reductase: Grail of Anti-Schistosome Drug within Reach?
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00072
Abstract: Species of the blood fluke Schistosoma are responsible for schistosomiasis, the second most common parasitic disease, which is prevalent particularly in poor communities. Under redox pressure, schistosomes survive in mammalian hosts with the help of… read more here.
Keywords: thioredoxin glutathione; inhibitors thioredoxin; glutathione reductase; drug ... See more keywords