New thiosemicarbazide-1,2,3-triazole hybrids as potent α-glucosidase inhibitors: Design, synthesis, and biological evaluation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.04.082
Abstract: Abstract A new series of thiosemicarbazide-1,2,3-triazole hybrids 10a-o has been synthesized, characterized by 1H NMR, 13C NMR, and screened for their in vitro α-glucosidase inhibitory activity. All of the synthesized compounds displayed excellent α-glucosidase inhibitory activity… read more here.
Keywords: hybrids potent; new thiosemicarbazide; potent glucosidase; compound 10h ... See more keywords
Modification of Diphenylphosphorylacetic Hydrazide with Thiosemicarbazide and Triazole Units
Sign Up to like & getrecommendations! Published in 2017 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363217120076
Abstract: Thiosemicarbazides of diphenylphosphorylacetic acid and their cyclic derivatives have been synthesized. Functionalization of the obtained 1,2,4-triazole-3-thiones with ethyl 2-bromoacetate at the sulfur atom has been carried out, the obtained esters have been transformed into the… read more here.
Keywords: hydrazide thiosemicarbazide; diphenylphosphorylacetic hydrazide; chemistry; modification diphenylphosphorylacetic ... See more keywords