Synthesis, structure and antiproliferative activity of organometallic iridium(III) complexes containing thiosemicarbazone ligands
Sign Up to like & getrecommendations! Published in 2017 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.3610
Abstract: A series of half-sandwich iridium complexes (1–4) with thiosemicarbazone ligands in two types of coordination modes were synthesized and characterized. The molecular structures of compounds 1, 2 and 3 were determined using single-crystal X-ray diffraction… read more here.
Keywords: iridium; thiosemicarbazone ligands; synthesis structure; structure antiproliferative ... See more keywords
Anti-proliferative effects of copper(II) complexes with hydroxyquinoline-thiosemicarbazone ligands.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.01.031
Abstract: The possibility to influence the physiological concentration of copper ions through the careful choice of ligands is emerging as a novel intriguing strategy in the treatment of pathologies such as cancer and Alzheimer. Thiosemicarbazones play… read more here.
Keywords: proliferative effects; anti proliferative; copper; thiosemicarbazone ligands ... See more keywords