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Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26601
Abstract: Mutations in p53 gene are one of the hallmarks of tumor development. Specific targeting of mutant p53 protein has a promising role in cancer therapeutics. Our preliminary observation showed destabilization of mutant p53 protein in…
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Keywords:
p53 protein;
bag3;
treatment;
thiostrepton ... See more keywords
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Published in 2021 at "Gynecologic Oncology"
DOI: 10.1016/s0090-8258(21)01181-1
Abstract: Objectives: Epithelial ovarian cancer (EOC) is a challenging disease due to chemoresistance, and short-term recurrence. Chemoresistance to anti-cancer drugs substantially reduces survival in EOC. In this study, we showed that chemoresistance to lapatinib (a dual…
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Keywords:
foxm1 egfr;
egfr erbb2;
egfr;
thiostrepton ... See more keywords
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Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1104454
Abstract: Due to the increased resistance to all available antibiotics and the lack of vaccines, Neisseria gonorrhoeae (the gonococcus) poses an urgent threat. Although the mechanisms of virulence and antibiotic resistance have been largely investigated in…
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Keywords:
antibiotic resistance;
neisseria gonorrhoeae;
resistance;
virulence ... See more keywords
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Published in 2019 at "Oncology Reports"
DOI: 10.3892/or.2019.7225
Abstract: Breast cancer is the most common type of malignancies in women worldwide, and genotoxic chemotherapeutic drugs are effective by causing DNA damage in cancer cells. However, >90% of patients with metastatic cancer are resistant to…
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Keywords:
forkhead box;
thiostrepton;
breast cancer;
cancer cells ... See more keywords