Synthesis of Promising Biguanide Derivatives Bearing Urea/Thiourea as Type II Antidiabetic Agents
Sign Up to like & getrecommendations! Published in 2025 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.70150
Abstract: Novel biguanide hydrochloride salts were synthesized through the reaction of N‐substituted‐semi(thiosemi)carbazides with cyanoguanidine in an acidic medium. Antidiabetic properties of the synthesized biguanides were evaluated for their antidiabetic properties. All biguanide compounds showed promising effects,… read more here.
Keywords: synthesis promising; biguanide derivatives; derivatives bearing; thiourea ... See more keywords
Thiourea derivatives inhibit key diabetes‐associated enzymes and advanced glycation end‐product formation as a treatment for diabetes mellitus
Sign Up to like & getrecommendations! Published in 2022 at "IUBMB Life"
DOI: 10.1002/iub.2699
Abstract: This study was designed to screen novel thiourea derivatives against different enzymes, such as α‐amylase, α‐glucosidase, protein tyrosine phosphatase 1 B, and advanced glycated end product (AGEs). A cytotoxicity analysis was performed using rat L6… read more here.
Keywords: thiourea derivatives; end product; thiourea; derivatives inhibit ... See more keywords
Computational and experimental structural analysis of 3-benzoyl-1,1-dimethyl-thiourea and its polymorph
Sign Up to like & getrecommendations! Published in 2025 at "Structural Chemistry"
DOI: 10.1007/s11224-025-02489-4
Abstract: 3-benzoyl-1,1-dimethyl-thiourea (3BDMT) is an important derivative of thiourea that has potential applications in different fields like medical, coordination and organic chemistry, pharmaceuticals, material science, and agriculture. This potential remains underexplored, leading to a lack of… read more here.
Keywords: chemistry; thiourea; new form; geometry ... See more keywords
Synthesis, Growth, and Characterization of a New Thiourea and Bismuth Chloride Complex with Excellent Nonlinear Optical Properties
Sign Up to like & getrecommendations! Published in 2018 at "Transactions of Tianjin University"
DOI: 10.1007/s12209-018-0148-4
Abstract: Crystals of a new organometallic nonlinear optical (NLO) compound, di-μ-chloro-bis[chlorotri(thiourea)bismuth(III)]-pentachloro(thiourea)bismuth-ate(III) (DCBPB), have been successfully grown from formic acid aqueous solutions of thiourea and bismuth chloride by a slow evaporation technique. The crystal structure and atomic… read more here.
Keywords: bismuth chloride; nonlinear optical; thiourea; thiourea bismuth ... See more keywords
Synthesis and anticancer activity of bis-benzo[d][1,3]dioxol-5-yl thiourea derivatives with molecular docking study.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103088
Abstract: New thiourea derivatives incorporating two benzo[d][1,3]dioxol-5-yl moieties have been synthesized through the reaction of two molecules of benzo[d][1,3]dioxol-5-yl isothiocyanate with one molecule of various diamino derivatives. The synthesized compounds were examined for their cytotoxic effects… read more here.
Keywords: dioxol thiourea; benzo dioxol; bis benzo; thiourea ... See more keywords
Insight into the binding affinity of thiourea in the calcium binding pocket of proteinase K, through high resolution X-ray crystallography.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103443
Abstract: Proteinase K is a stable serine protease, crystallized and extensively used in the study of molecular interactions at the atomic level. During the current study, crystal structure of proteinase K with thiourea (TU) was solved… read more here.
Keywords: calcium binding; thiourea; proteinase; calcium ... See more keywords
Decontamination of Hg(II) from aqueous solution using polyamine-co-thiourea inarched chitosan gel derivatives.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.02.101
Abstract: Ethylenediamine (EDA), triethylenetetramine (TETA) and tetraethylenepentamine (TEPA) had been successfully introduced into the structure of thiourea (TC) modified chitosan (CS) by using formaldehyde as linkage, respectively. The resulted materials, TC-CS, TC-EDA-CS, TC-TETA-CS, and TC-TEPA-CS were… read more here.
Keywords: decontamination aqueous; adsorption; solution using; thiourea ... See more keywords
Thiourea-assisted coating of dispersed copper electrocatalysts on Si photocathodes for solar hydrogen production
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Energy Chemistry"
DOI: 10.1016/j.jechem.2019.02.012
Abstract: Abstract Photoelectrochemical water splitting can convert solar energy into clean hydrogen energy for storage. It is desirable to explore non-precious electrocatalysts for practical applications of a photoelectrode in a large scale. Here, we developed a… read more here.
Keywords: dispersed copper; hydrogen; thiourea assisted; assisted coating ... See more keywords
In-situ synthesis of highly nitrogen, sulfur co-doped carbon nanosheets from melamine-formaldehyde-thiourea resin with improved cycling stability and energy density for supercapacitors
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Power Sources"
DOI: 10.1016/j.jpowsour.2019.01.092
Abstract: Abstract For fabricating porous carbon nanosheets possessing ultra-high content (ca. 20 at%) of heteroatoms and large specific surface area, we propose a feasible and valid hard template strategy via one-step in situ pyrolysis of crosslinking polymer… read more here.
Keywords: carbon nanosheets; melamine formaldehyde; formaldehyde thiourea; carbon ... See more keywords
Antioxidant activity of thiourea derivatives: An experimental and theoretical study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.117149
Abstract: Abstract Antioxidant ability of thiourea derivatives was characterized based on the measurement of the color change of 2,2-diphenyl-1-picrylhydrazyl (DPPH ) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS +) when reacting with the studied compounds. The values of IC50DPPH/ [IC50ABTS]… read more here.
Keywords: derivatives experimental; experimental theoretical; thiourea derivatives; activity thiourea ... See more keywords
Investigation of spectroscopic, reactive, transport and docking properties of 1-(3,4-dichlorophenyl)-3-[3-(trifluoromethyl)phenyl]thiourea (ANF-6): Combined experimental and computational study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.01.016
Abstract: Abstract The wavenumbers, molecular structure, molecular electrostatic potential, nonlinear optical properties and natural bond orbital analysis of a thiourea derivative, 1-(3,4-dichlorophenyl)-3-[3-(trifluoromethyl)phenyl]thiourea (ANF-6) were reported. For the title molecule, HOMO is all over the molecule except… read more here.
Keywords: thiourea; study; phenyl thiourea; dichlorophenyl trifluoromethyl ... See more keywords