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Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000468
Abstract: The synthesis of a new small library of molecules containing bis‐urea/thiourea pendants in lysine conjugated to three different heterocycles is described. The heterocycles used in this study have benzisoxazole/piperazine/piperidine units. After a detailed antimicrobial, antioxidant,…
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Keywords:
directed therapeutics;
thiourea derivatives;
urea thiourea;
therapeutics urea ... See more keywords
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Published in 2022 at "IUBMB Life"
DOI: 10.1002/iub.2699
Abstract: This study was designed to screen novel thiourea derivatives against different enzymes, such as α‐amylase, α‐glucosidase, protein tyrosine phosphatase 1 B, and advanced glycated end product (AGEs). A cytotoxicity analysis was performed using rat L6…
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Keywords:
thiourea derivatives;
end product;
thiourea;
derivatives inhibit ... See more keywords
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Published in 2021 at "Pest management science"
DOI: 10.1002/ps.6758
Abstract: BACKGROUND Devastating plant virus diseases leaving a bad harvest and lower quality of crops have made feeding beyond 7 billion populations a huge challenge. Nevertheless, growing resistance and cross resistance of crop protection agents lead…
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Keywords:
self assembly;
mosaic virus;
virus;
virus particles ... See more keywords
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Published in 2019 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-019-01617-2
Abstract: Abstractp-Sulphonic-N-propionyl aniline 3 was produced from sulphanilic acid with propionic acid under reflux for 2 h, then the compound 3 reacted with thionyl chloride and the corresponding imidoyl chloride 4 was obtained. When imidoyl chloride 4…
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Keywords:
antimicrobial evaluation;
evaluation new;
synthesis antimicrobial;
new glucosylimino ... See more keywords
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Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103088
Abstract: New thiourea derivatives incorporating two benzo[d][1,3]dioxol-5-yl moieties have been synthesized through the reaction of two molecules of benzo[d][1,3]dioxol-5-yl isothiocyanate with one molecule of various diamino derivatives. The synthesized compounds were examined for their cytotoxic effects…
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Keywords:
dioxol thiourea;
benzo dioxol;
bis benzo;
thiourea ... See more keywords
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Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.07.082
Abstract: The mutually corroborated density functional theory (DFT) and molecular dynamics (MD) simulation methodology were employed to evaluate the inhibition performance of three thiourea derivatives (Inh1, Inh2, and Inh3) on carbon steel corrosion. Experimental results have…
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Keywords:
steel corrosion;
molecular dynamics;
dft molecular;
carbon steel ... See more keywords
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Published in 2017 at "Journal of King Saud University - Science"
DOI: 10.1016/j.jksus.2016.12.006
Abstract: Abstract A new series of 1-(4-substitutedphenyl)-3-(4-(4,6-dimethyl-6H-1,3-thiazin-2-yl)phenylsulfon-yl)urea/thiourea (3a–l) derivatives were synthesized and screened for anticonvulsant activity by maximal electro shock (MES) and pentylenetetrazole (PTZ) induced convulsant model. All the derivatives were evaluated for neurotoxicity measures by…
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Keywords:
thiourea derivatives;
anticonvulsant activity;
urea thiourea;
dimethyl thiazin ... See more keywords
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Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.117149
Abstract: Abstract Antioxidant ability of thiourea derivatives was characterized based on the measurement of the color change of 2,2-diphenyl-1-picrylhydrazyl (DPPH ) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS +) when reacting with the studied compounds. The values of IC50DPPH/ [IC50ABTS]…
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Keywords:
derivatives experimental;
experimental theoretical;
thiourea derivatives;
activity thiourea ... See more keywords
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Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128302
Abstract: Abstract Synthesis of some thiourea derivatives have been achieved by using ultrasound, the compounds have been characterised using IR, NMR, GC-MS and elemental analysis. The single crystal X-ray structure of N-[(benzyloxy)methanethioyl]benzamide (IV), 1-benzoyl-3-(2-hydroxyethyl)thiourea (V) and…
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Keywords:
ultrasound promoted;
promoted synthesis;
characterization computational;
thiourea derivatives ... See more keywords
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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06718
Abstract: This work demonstrates the optimization of an efficient, mild, and environmentally friendly synthetic approach to access a diverse library of N-naphthoyl thioureas. These derivatives could be exploited as precursor scaffolds for designing valuable heterocycles with…
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Keywords:
naphthoyl thiourea;
derivatives efficient;
thiourea derivatives;
ultrasonic assisted ... See more keywords
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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04671
Abstract: Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is considered a global public health concern since it causes high morbidity and mortality. Recently, it has been reported that repurposed anti-COVID-19 drugs might interact with multidrug…
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Keywords:
multidrug resistance;
transporter;
thiourea derivatives;
abcb1 ... See more keywords