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Published in 2017 at "Chemical Papers"
DOI: 10.1007/s11696-017-0273-x
Abstract: A simple convenient protocol for the synthesis of methyl 2-[3-(2-(substituted phenyl)quinazolin-4-yl)thioureido] alkanoates is described. It involves the domino reaction of various amino acid esters with imidoylisothiocyanates in ethyl acetate to afford quinazoline thiourea derivatives in…
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Keywords:
thioureido alkanoates;
domino synthesis;
quinazolin thioureido;