Synthesis of 6-unsubstituted 2-oxo, 2-thioxo, and 2-amino-3,4-dihydropyrimidines and their antiproliferative effect on HL-60 cells
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DOI: 10.1016/j.tetlet.2020.151967
Abstract: Abstract A general and efficient synthetic method for 6-unsubstituted 3,4-dihydropyrimidin-2(1H)-thiones 6 and -ones 7 has been developed. In three-component reactions, the reactivity of reagents serving as the C5–C6 fragment of the dihydropyrimidine ring was compared.… read more here.
Keywords: unsubstituted oxo; antiproliferative effect; thioxo amino; effect ... See more keywords