Catalyst-free glycerol-mediated green synthesis of 5′-thioxospiro[indoline-3,3′-[1,2,4]triazolidin]-2-ones/spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones
Sign Up to like & getrecommendations! Published in 2017 at "Synthetic Communications"
DOI: 10.1080/00397911.2017.1359844
Abstract: ABSTRACT The development of new catalyst-free green and efficient protocol to access 5′-thioxospiro[indoline-3,3′-[1,2,4]triazolidin]-2-ones/spiro[indoline-3,3′-[1,2,4]triazolidine]-2,5′-diones, potential privileged scaffolds for drug discovery, is disclosed. Key feature of this methodology is the dual use of glycerol—a recyclable, bioorganic compound,… read more here.
Keywords: ones spiro; indoline triazolidin; spiro indoline; thioxospiro indoline ... See more keywords