Enhanced Activities of δ Subunit-containing GABAA Receptors Blocked Spinal Long-term Potentiation and Attenuated Formalin-induced Spontaneous Pain
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DOI: 10.1016/j.neuroscience.2017.12.002
Abstract: The δ subunit-containing γ-Aminobutyric acid type A receptors (δ-GABAARs) are located at extrasynaptic sites and persistently active in the control of neuronal excitability. Here we recorded primary afferent C fiber-evoked field potentials in the superficial… read more here.
Keywords: term potentiation; formalin; thip; subunit containing ... See more keywords
Effects of early‐life exposure to THIP on brainstem neuronal excitability in the Mecp2‐null mouse model of Rett syndrome before and after drug withdrawal
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DOI: 10.14814/phy2.13110
Abstract: Rett syndrome (RTT) is mostly caused by mutations of the X‐linked MECP2 gene. Although the causal neuronal mechanisms are still unclear, accumulating experimental evidence obtained from Mecp2−/Y mice suggests that imbalanced excitation/inhibition in central neurons… read more here.
Keywords: thip; mecp2; early life; mecp2 mice ... See more keywords