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   Articles with "thk 5351" as a keyword



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Tau accumulation in two patients with frontotemporal lobe degeneration showing different types of aphasia using 18F-THK-5351 positron emission tomography: a case report

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recommendations! Published in 2017 at "International Psychogeriatrics"

DOI: 10.1017/s1041610217002277

Abstract: ABSTRACT Tau deposits in Alzheimer's disease and corticobasal syndrome have been reported using 18F-THK-5351 positron emission tomography (PET). To our knowledge, our study is the first to demonstrate tau deposits in patients with frontotemporal lobe… read more here.

Keywords: 18f thk; using 18f; thk 5351; positron emission ... See more keywords
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Clinical Evaluation of 18F-PI-2620 as a Potent PET Radiotracer Imaging Tau Protein in Alzheimer Disease and Other Neurodegenerative Diseases Compared With 18F-THK-5351

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recommendations! Published in 2020 at "Clinical Nuclear Medicine"

DOI: 10.1097/rlu.0000000000003261

Abstract: Purpose PET is a useful tool for detecting the presence and extent of brain tau accumulation. However, most first-generation tau PET tracers are limited for high off-target binding and detection of tau in non-Alzheimer disease… read more here.

Keywords: 18f thk; 18f 2620; tau; alzheimer disease ... See more keywords
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Progression of logopenic aphasia to frontotemporal dementia in an amyloid β‐negative and 18F‐THK‐5351‐positive patient

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recommendations! Published in 2019 at "Psychogeriatrics"

DOI: 10.1111/psyg.12396

Abstract: Logopenic aphasia (logopenic variant primary progressive aphasia (lvPPA)) is considered to be the third type of primary progressive aphasia (PPA). The other two types of PPA are progressive nonfluent aphasia (nonfluent/agrammatic variant PPA) and semantic… read more here.

Keywords: frontotemporal dementia; thk 5351; logopenic aphasia; patient ... See more keywords
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Visualization of ischemic stroke-related changes on 18F-THK-5351 positron emission tomography

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recommendations! Published in 2018 at "EJNMMI Research"

DOI: 10.1186/s13550-018-0417-1

Abstract: BackgroundThe 18F-THK-5351 radiotracer has been used to detect the in vivo tau protein distribution in patients with tauopathy, such as Alzheimer’s disease and corticobasal syndrome. In addition, 18F-THK-5351 can also monitor neuroinflammatory process due to… read more here.

Keywords: 5351 positron; ischemic stroke; thk 5351; 18f thk ... See more keywords
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Intra-individual correlations between quantitative THK-5351 PET and MRI-derived cortical volume in Alzheimer’s disease differ according to disease severity and amyloid positivity

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recommendations! Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0226265

Abstract: Purpose To assess the in vivo whole-brain relationship between uptake of [18F]THK-5351 on PET and cortical atrophy on structural MRI according to the presence and severity of Alzheimer’s disease (AD). Materials and methods Sixty-five participants… read more here.

Keywords: mri; cortical volume; thk 5351; disease ... See more keywords