Potential Use of 18F-THK5351 PET to Identify Wallerian Degeneration of the Pyramidal Tract Caused by Cerebral Infarction.
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DOI: 10.1097/rlu.0000000000001868
Abstract: A 41-year-old man underwent F-THK5351 PET 2 years after a right middle cerebral artery infarction. F-THK5351 PET imaging revealed intense radioligand uptake along the ipsilateral pyramidal tract from the corona radiata to the medulla; intense… read more here.
Keywords: pyramidal tract; thk5351; thk5351 pet;
Distribution Pattern of the Monoamine Oxidase B Ligand, 18F-THK5351, in the Healthy Brain
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DOI: 10.1097/rlu.0000000000004272
Abstract: Background 18F-THK5351 PET estimates the concentrations of monoamine oxidase B (MAO-B) that are preferentially located in astrocytes and can be used to visualize and quantify ongoing astrogliosis. To study images of astrogliosis in neurological disorders,… read more here.
Keywords: distribution pattern; 18f thk5351; thk5351; thk5351 healthy ... See more keywords
Increased Uptake of 18F-THK5351 in Glioblastoma But Not in Metastatic Brain Tumor.
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DOI: 10.1097/rlu.0000000000005909
Abstract: 18F-THK5351 was developed as a tracer with high binding affinity and selectivity for tau protein. However, its off-target binding to monoamine oxidase B (MAO-B), an enzyme highly expressed in astrocytes, has also been demonstrated. In… read more here.
Keywords: brain tumor; metastatic brain; 18f thk5351; thk5351 ... See more keywords