Aldose Reductase Mediates NLRP3 Inflammasome‐Initiated Innate Immune Response in Hyperglycemia‐Induced Thp1 Monocytes and Male Mice
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DOI: 10.1210/en.2017-00294
Abstract: &NA; Despite recent studies that show oxidative stress‐generated reactive oxygen species (ROS) regulate NOD‐like receptor family pyrin domain containing 3 (NLRP3) inflammasome‐mediated innate immune response in various diabetic complications, the mechanism by which ROS activate… read more here.
Keywords: thp1 monocytes; hyperglycemia induced; immune response; nlrp3 inflammasome ... See more keywords