Reshaping the Energy Landscape Transforms the Mechanism and Binding Kinetics of DNA Threading Intercalation.
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DOI: 10.1021/acs.biochem.7b01036
Abstract: Molecules that bind DNA via threading intercalation show high binding affinity as well as slow dissociation kinetics, properties ideal for the development of anticancer drugs. To this end, it is critical to identify the specific… read more here.
Keywords: dna threading; mechanism; dna; binding kinetics ... See more keywords