Three Is a Crowd - New Insights into Rosetting in Plasmodium falciparum.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in parasitology"
DOI: 10.1016/j.pt.2016.12.012
Abstract: The intracellular malaria parasites extensively modify host erythrocytes to allow nutrient uptake, ensure homeostasis, and evade the host's immune response. To achieve this, the parasite exports several proteins to the erythrocyte surface. In Plasmodium falciparum,… read more here.
Keywords: plasmodium falciparum; crowd new; three crowd; pathology ... See more keywords
Three's a crowd – stabilisation, structure, and applications of DNA triplexes
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc01793h
Abstract: DNA is a strikingly flexible molecule and can form a variety of secondary structures, including the triple helix, which is the subject of this review. The DNA triplex may be formed naturally, during homologous recombination,… read more here.
Keywords: dna; dna triplexes; three crowd; crowd stabilisation ... See more keywords
When three is not a crowd: trispecific antibodies for enhanced cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.81494
Abstract: Despite the clinical success of the first bispecific antibody approved by the FDA against B cell malignancies (blinatumomab), many obstacles remain such as dosing, treatment resistance, and modest efficacy in solid tumors. To overcome these… read more here.
Keywords: multispecific antibodies; three crowd; crowd trispecific; trispecific antibodies ... See more keywords