Comparing non-occupational post-exposure prophylaxis drug regimens for HIV: insights from a linked HIV surveillance system.
Sign Up to like & getrecommendations! Published in 2017 at "Sexual health"
DOI: 10.1071/sh16132
Abstract: Background International non-occupational post-exposure prophylaxis (NPEP) guidelines recommend routine use of three drug NPEP regimens, despite absence of evidence for greater prevention efficacy compared with two drug regimens. This study examines the potential for excess… read more here.
Keywords: drug npep; drug regimens; exposure prophylaxis; three drug ... See more keywords
P-566. Long-term virologic outcomes of oral two-drug vs three-drug antiretroviral regimens in children, adolescents and adults living with HIV
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.764
Abstract: Abstract Background Despite the availability and efficacy of two-drug regimens (2DR) for HIV treatment, three-drug regimens (3DR) are mostly used by people with HIV (PWH). We evaluated virologic outcomes of initiating or switching to a… read more here.
Keywords: hiv; regimen initiation; drug; three drug ... See more keywords
Uptake and effectiveness of two-drug compared to three-drug antiretroviral Regimens among HIV-positive Individuals in Europe.
Sign Up to like & getrecommendations! Published in 2019 at "AIDS"
DOI: 10.1097/qad.0000000000002320
Abstract: OBJECTIVE To assess the use of two-drug antiretroviral regimens (2DR) and virologic and immunologic outcomes compared to three-drug regimens (3DR) in the EuroSIDA cohort. DESIGN Multicentre, prospective cohort study. METHODS Logistic regression was used to… read more here.
Keywords: three drug; drug; two drug; antiretroviral regimens ... See more keywords
Three-Drug Regimen Bests Chemo in NSCLC.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-nb2021-0380
Abstract: A three-drug regimen containing the CTLA4 inhibitor tremelimumab plus the PD-L1 inhibitor durvalumab and chemotherapy may be an effective first-line treatment strategy for patients with metastatic non-small cell lung cancer. In the phase III POSEIDON… read more here.
Keywords: three drug; drug regimen; chemo nsclc; bests chemo ... See more keywords
Efficacy of Three-Drug Induction Chemotherapy Followed by Preoperative Chemoradiation in Patients with Localized Gastric Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Oncology"
DOI: 10.1159/000506519
Abstract: Background: Preoperative induction chemotherapy followed by chemoradiation yields better R0 resection rates, pathologic complete response (pCR) rates and improved survival for localized gastric adenocarcinoma (GAC). We report the effect of three-drug induction chemotherapy on a… read more here.
Keywords: three drug; chemotherapy followed; induction; induction chemotherapy ... See more keywords
Efficacy of Lenalidomide Based Three Drug Versus Two Drug Regimen for Relapsed Multiple Myeloma: A Systematic Review and Meta-Analysis of Randomized Trials
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-111930
Abstract: Introduction: Survival of patients with multiple myeloma (MM) has improved over the last decade, mainly due to advent of newer drugs, three drug based induction, high dose chemotherapy consolidation and routine use of maintenance therapy… read more here.
Keywords: myeloma; three drug; drug; multiple myeloma ... See more keywords
In multiple myeloma patients, autologous stem cell transplants abrogate the difference of treating them with two or three drug combinations: Real world data from a single institution in a middle-income country.
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-7604
Abstract: Background: Currently, the standard treatment of MM is a three-drug regimen that includes immunomodulators, corticosteroids, and proteasome inhibitors, followed by an autologous stem cell transplant. Before the introduction of proteasome inhibitors in 2003, the treatment… read more here.
Keywords: treatment; single institution; therapy; stem cell ... See more keywords
When more is less: Emergent suppressive interactions in three-drug combinations
Sign Up to like & getrecommendations! Published in 2017 at "BMC Microbiology"
DOI: 10.1186/s12866-017-1017-3
Abstract: BackgroundIn drug-drug interactions, there are surprising cases in which the growth inhibition of bacteria by a single antibiotic decreases when a second antibiotic is added. These interactions are termed suppressive and have been argued to… read more here.
Keywords: emergent suppressive; interactions three; three drug; drug ... See more keywords
Virological and Immunological Outcomes of an Intensified Four-Drug versus a Standard Three-Drug Antiretroviral Regimen, Both Integrase Strand Transfer Inhibitor-Based, in Primary HIV Infection
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15040403
Abstract: The optimal therapeutic approach for primary HIV infection (PHI) is still debated. We aimed to compare the viroimmunological response to a four- versus a three-drug regimen, both INSTI-based, in patients with PHI. This was a… read more here.
Keywords: primary hiv; drug; hiv infection; three drug ... See more keywords