Three Key Regions in Hemagglutinin Determine Binding Selectivity and Stability: Insights into Antiviral Drug Design.
Sign Up to like & getrecommendations! Published in 2025 at "Biochemistry"
DOI: 10.1021/acs.biochem.5c00586
Abstract: The receptor binding domain of hemagglutinin (HA) of influenza viruses contains three key regions for binding its endogenous carbohydrate receptors: loop-130, helix-190, and loop-220. To effectively predict the binding of HA with endogenous glycan ligands… read more here.
Keywords: drug design; three key; hypothesis; antiviral drug ... See more keywords
Stabilities of Three Key Biological Trisulfides with Implications for Their Roles in the Release of Hydrogen Sulfide and Bioaccumulation of Sulfane Sulfur
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DOI: 10.1021/acsomega.2c00736
Abstract: Trisulfides and higher polysulfides are important in the body due to their function as key reservoirs of sulfane sulfur and their rapid reactions to release persulfides. Recent work has shown that persulfides act as powerful… read more here.
Keywords: release hydrogen; spectroscopy; hydrogen sulfide; sulfur ... See more keywords
Three key issues for determining competence in a system of assessment
Sign Up to like & getrecommendations! Published in 2020 at "Medical Teacher"
DOI: 10.1080/0142159x.2020.1804540
Abstract: Abstract There is widespread agreement that medical education should include multi-source, multi-method, and multi-purpose forms of assessment and thus should move towards cohesive systems of assessment. One possibility that fits comfortably with a system of… read more here.
Keywords: competence; competency; key issues; determining competence ... See more keywords
Destination design: identifying three key co-design strategies
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DOI: 10.1080/13683500.2024.2332495
Abstract: ABSTRACT Collaborative approaches to destination design require conscious and reflexive stakeholder involvement in activities and decision making. Design science studies such participatory processes by observing design teams in practice. From these observations, scientists have identified… read more here.
Keywords: three key; key design; design; destination design ... See more keywords
Three Key considerations for biodiversity conservation in multilateral agreements
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DOI: 10.1111/conl.12764
Abstract: It is nearly three decades since the world recognized the need for a global multilateral treaty aiming to address accelerating biodiversity loss. However, biodiversity continues to decline at a concerning rate. Drawing on lessons from… read more here.
Keywords: multilateral agreements; conservation; biodiversity; three key ... See more keywords
Optimization of Three Key Geometries of a Steam Ejector under Varied Primary Nozzle Geometries
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DOI: 10.3390/e25010015
Abstract: In this paper, three key geometrical dimensions such as XL3 (constant pressure mixing chamber length), D5 (diameter of the throat of the ejector), and XL5 (length of the throat of the ejector) were separately or… read more here.
Keywords: three key; key geometries; ejector performance; ejector ... See more keywords
Materials, machines, meanings: Possible design strategies to compensate three key shortages of distributed manufacturing
Sign Up to like & getrecommendations! Published in 2020 at "Strategic Design Research Journal"
DOI: 10.4013/sdrj.2020.13.19540
Abstract: This contribution starts by observing the low presence of “indie made”, distributed and digital fabrication based products in the everyday life of most people. We assume that this low presence is a result of limitations… read more here.
Keywords: design strategies; compensate three; strategies compensate; design ... See more keywords