Reversal of apixaban anticoagulation by four‐factor prothrombin complex concentrates in healthy subjects: a randomized three‐period crossover study
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DOI: 10.1111/jth.13815
Abstract: Essentials Prothrombin complex concentrates (PCCs) may reverse the effect of factor Xa (FXa) inhibitors. We conducted an open‐label, randomized, placebo‐controlled, three‐period crossover study in 15 subjects. Both PCCs rapidly reversed apixaban‐mediated decreases in mean endogenous… read more here.
Keywords: period crossover; crossover study; three period; complex concentrates ... See more keywords