Articles with "three preclinical" as a keyword



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Antiretroviral Penetration across Three Preclinical Animal Models and Humans in Eight Putative HIV Viral Reservoirs

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Published in 2019 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.01639-19

Abstract: For HIV cure strategies like “kick and kill” to succeed, antiretroviral (ARV) drugs must reach effective concentrations in putative viral reservoirs. We characterize penetration of six ARVs in three preclinical animal models and humans. We… read more here.

Keywords: animal models; preclinical animal; viral reservoirs; penetration ... See more keywords