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   Articles with "threonine" as a keyword



Evaluation of safe utilization of l-threonine for supplementation in healthy adults: a randomized double blind controlled trial

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recommendations! Published in 2025 at "Amino Acids"

DOI: 10.1007/s00726-025-03461-6

Abstract: l-threonine is used in dietary supplements and nutritional products ingested by healthy consumers. The objective of this study was to determine in a randomized double blind controlled clinical trial the safety and tolerability of l-threonine… read more here.

Keywords: supplementation; threonine; trial; randomized double ... See more keywords

Comparison of Zinc Sulfate and Zinc Threonine Based on Zn Bioavailability and Performance of Broiler Chicks.

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recommendations! Published in 2020 at "Biological trace element research"

DOI: 10.1007/s12011-020-02354-x

Abstract: The purpose of this study was to compare zinc sulfate and zinc threonine chelate based on Zn bioavailability and performance of broiler chicks. The study was conducted in a completely randomized design with 256 day-old Ross… read more here.

Keywords: zinc sulfate; zinc; zinc threonine; threonine chelate ... See more keywords

Flaviviridae viruses use a common molecular mechanism to escape nucleoside analogue inhibitors.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.03.068

Abstract: The RNA-dependent RNA polymerases of Flaviviridae viruses are crucial for replication. The Flaviviridae polymerase is organized into structural motifs (A-G), with motifs F, A, C and E containing interrogating, priming and catalytic substrate-interacting sites. Modified… read more here.

Keywords: flaviviridae viruses; analogue inhibitors; threonine; nucleoside analogue ... See more keywords

Progress in using threonine aldolases for preparative synthesis.

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recommendations! Published in 2018 at "Enzyme and microbial technology"

DOI: 10.1016/j.enzmictec.2018.07.004

Abstract: Three threonine aldolases (TAs) were cloned and overexpressed in Escherichia coli (Aeromonas jandaeil-allo-threonine aldolase, E. colil-threonine aldolase and Thermotoga maritimal-allo-threonine aldolase). A Design of Experiments strategy was used to identify optimal reaction conditions for each… read more here.

Keywords: threonine aldolase; threonine aldolases; aldolases preparative; threonine ... See more keywords

l-Threonine improves intestinal mucin synthesis and immune function of intrauterine growth-retarded weanling piglets.

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recommendations! Published in 2019 at "Nutrition"

DOI: 10.1016/j.nut.2018.07.114

Abstract: OBJECTIVES The aim of this study was to investigate the effects of dietary l-threonine supplementation on the growth performance, intestinal immune function, mucin synthesis, and goblet cell differentiation in weanling piglets with intrauterine growth retardation… read more here.

Keywords: threonine; weanling piglets; immune function; iugr ... See more keywords

Effects of genetic selection and threonine on meat quality in Pekin ducks

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recommendations! Published in 2020 at "Poultry Science"

DOI: 10.1016/j.psj.2019.10.059

Abstract: The present study was conducted to investigate the effects of genetic selection and threonine levels on meat quality in Pekin ducks. At 15 D of age, 192 lean ducks and 192 fatty ducks were selected… read more here.

Keywords: pufa; genetic selection; threonine; fatty ducks ... See more keywords
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Effects of low-crude protein diets supplemented with arginine, glutamine, threonine, and methionine on regulating nutrient absorption, intestinal health, and growth performance of Eimeria-infected chickens

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recommendations! Published in 2021 at "Poultry Science"

DOI: 10.1016/j.psj.2021.101427

Abstract: The study was conducted to evaluate the effects of low crude protein diets supplemented with arginine, glutamine, methionine, and/or threonine on apparent ileal digestibility of amino acids, intestinal morphology, intestinal permeability, gene expression of nutrient… read more here.

Keywords: arginine glutamine; methionine; threonine; crude protein ... See more keywords

Engineering Halomonas bluephagenesis for L-Threonine production.

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recommendations! Published in 2020 at "Metabolic engineering"

DOI: 10.1016/j.ymben.2020.04.004

Abstract: Halophilic Halomonas bluephagenesis (H. bluephagenesis), a chassis for cost-effective Next Generation Industrial Biotechnology (NGIB), was for the first time engineered to successfully produce L-threonine, one of the aspartic family amino acids (AFAAs). Five exogenous genes… read more here.

Keywords: production; halomonas bluephagenesis; bluephagenesis; threonine ... See more keywords

Poly(l-threonine-co-l-threonine Succinate) Thermogels for Sustained Release of Lixisenatide.

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recommendations! Published in 2024 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.4c00376

Abstract: Negatively charged poly(l-Thr-co-l-Thr succinate) (PTTs) was developed as a new thermogel. Aqueous PTT solutions underwent thermogelation over a concentration range of 6.0-8.3 wt %. Dynamic light scattering, FTIR, 1H NMR, and COSY spectra revealed the… read more here.

Keywords: threonine; initial burst; release; ptts ... See more keywords

Engineering Escherichia coli for l-Threonine Hyperproduction Based on Multidimensional Optimization Strategies.

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recommendations! Published in 2024 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.4c07607

Abstract: Exploring effective remodeling strategies to further improve the productivity of high-yield strains is the goal of biomanufacturing. However, the lack of insight into host-specific metabolic networks prevents timely identification of useful engineering targets. Here, multidimensional… read more here.

Keywords: escherichia coli; threonine; coli threonine; engineering ... See more keywords

Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth.

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recommendations! Published in 2022 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.2c00327

Abstract: Recent high-resolution structures of alpha-synuclein (aSyn) fibrils offer promise for rational approaches to drug discovery for Parkinson's disease and Lewy body dementia. Harnessing the first such structures, we previously used molecular dynamics and free energy… read more here.

Keywords: fibril growth; alpha synuclein; threonine cavities; threonine ... See more keywords