Small peptide inhibitor from the sequence of RUNX3 disrupts PAK1–RUNX3 interaction and abrogates its phosphorylation-dependent oncogenic function
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DOI: 10.1038/s41388-021-01927-x
Abstract: P21 Activated Kinase 1 (PAK1) is an oncogenic serine/threonine kinase known to play a significant role in the regulation of cytoskeleton and cell morphology. Runt-related transcription factor 3 (RUNX3) was initially known for its tumor… read more here.
Keywords: phosphorylation; threonine 209; runx3; small peptide ... See more keywords