O-GlcNAcylation of MORC2 at threonine 556 by OGT couples TGF-β signaling to breast cancer progression
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DOI: 10.1038/s41418-021-00901-0
Abstract: MORC family CW-type zinc finger 2 (MORC2) is a newly identified chromatin-remodeling enzyme involved in DNA damage response and gene transcription, and its dysregulation has been linked with Charcot-Marie-Tooth disease, neurodevelopmental disorder, and cancer. Despite… read more here.
Keywords: cancer; breast cancer; glcnacylation; threonine 556 ... See more keywords