Long noncoding RNA THRIL promotes foam cell formation and inflammation in macrophages
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DOI: 10.1002/cbin.11934
Abstract: Tumor necrosis factor‐α (TNF‐α) and heterogenous nuclear ribonucleoprotein L (hnRNPL)‐related immunoregulatory lincRNA (THRIL) is a long noncoding RNA (lncRNA) involved in various inflammatory diseases. However, its role in atherosclerosis is not known. In this study,… read more here.
Keywords: inflammation; thril; foam cell; rna ... See more keywords
Long Non-coding RNA THRIL Mediates Cell Growth and Inflammatory Response of Fibroblast-Like Synoviocytes by Activating PI3K/AKT Signals in Rheumatoid Arthritis
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DOI: 10.1007/s10753-020-01189-x
Abstract: The present study explored the possible functions and the underlying mechanism of tumor necrosis factor-α (TNF-α) and heterogeneous nuclear ribonucleoprotein L (hnRNPL)–related immunoregulatory lncRNA plasmacytoma variant translocation 1 (THRIL) in rheumatoid arthritis (RA). Serum samples… read more here.
Keywords: fibroblast like; pi3k akt; rheumatoid arthritis; thril ... See more keywords
Upregulated lncRNA THRIL/TNF-α Signals Promote Cell Growth and Predict Poor Clinical Outcomes of Osteosarcoma
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DOI: 10.2147/ott.s235798
Abstract: Background The immunosuppressive facet and tumorigenic role of TNF-α have been revealed in osteosarcoma (OS). Long noncoding RNA THRIL is identified to regulate TNF-α expression and participates in immune response. Thus, investigations on the clinical… read more here.
Keywords: thril tnf; tnf signals; tnf; thril ... See more keywords