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   Articles with "thrombin" as a keyword



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Thrombosis‐Responsive Thrombolytic Coating Based on Thrombin‐Degradable Tissue Plasminogen Activator (t‐PA) Nanocapsules

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recommendations! Published in 2017 at "Advanced Functional Materials"

DOI: 10.1002/adfm.201703934

Abstract: Surface modification with bioactive agents capable of combating thrombosis is a widely used strategy for developing antithrombotic biomaterials. However, exposure of the blood to the antithrombotic agent on the material surface may cause hemostatic disorders… read more here.

Keywords: thrombosis responsive; activator; surface; responsive thrombolytic ... See more keywords
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Treatment patterns and outcomes of octogenarian patients with acute myeloid leukemia

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recommendations! Published in 2019 at "American Journal of Hematology"

DOI: 10.1002/ajh.25464

Abstract: REFERENCES 1. Di Nisio M, Middeldorp S, Büller HR. Direct thrombin inhibitors. New Engl J Med. 2005;353:1028-1040. 2. Lewis BE, Wallis DE, Berkowitz SD, et al. Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation.… read more here.

Keywords: https doi; pathol; doi org; https ... See more keywords
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Ecarin based coagulation testing

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recommendations! Published in 2020 at "American Journal of Hematology"

DOI: 10.1002/ajh.25852

Abstract: Ecarin is derived from venom of Echis carinatus, and will activate prothrombin into meizothrombin which will then cleave fibrinogen to result in clot formation. Ecarin based testing has been described for decades, but these assays… read more here.

Keywords: coagulation testing; coagulation; ecarin based; based coagulation ... See more keywords
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Clinical Issues-October 2022.

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recommendations! Published in 2022 at "AORN journal"

DOI: 10.1002/aorn.13791

Abstract: Verifying patient identity before blood product administration Key words: patient identification, patient verification, blood transfusion, blood management, wristband. Surgical site infection risk with allogeneic blood administration Key words: patient blood management, restrictive transfusion triggers, allogeneic… read more here.

Keywords: october 2022; clinical issues; issues october; blood ... See more keywords
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Incorporation of a Multi-Valent Aptamer into Electrochemical Biosensors to Achieve an Improved Performance for Thrombin Analysis in Blood Serum.

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recommendations! Published in 2022 at "ChemPlusChem"

DOI: 10.1002/cplu.202200325

Abstract: The electrochemical aptamer-based (E-AB) biosensor usually has a long reaction time when detecting thrombin. This work reports the design of an E-AB biosensor with dual recognition sites to quickly detect thrombin. Specifically, two specific recognition… read more here.

Keywords: performance; serum; tba sensor; thrombin ... See more keywords
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Rapid screening and identification of anticoagulation component from carthami flos by two dimensional thrombin affinity chromatography combined with HPLC-MS/MS.

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recommendations! Published in 2021 at "Journal of separation science"

DOI: 10.1002/jssc.202100092

Abstract: Carthami flos, commonly known as Honghua in China, is the dried floret of safflower and widely acknowledged as a blood stasis promoting herb. The study aimed at investigating the relationship between thrombin and carthami flos… read more here.

Keywords: carthami flos; thrombin; affinity chromatography; thrombin affinity ... See more keywords
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Polypyrrole-palladium nanocomposite as a high-efficiency transducer for thrombin detection with liposomes as a label

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recommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-021-03673-1

Abstract: Sensitive and selective determination of protein biomarkers with high accuracy often remains a great challenge due to their existence in the human body at an exceptionally low concentration level. Therefore, sensing mechanisms that are easy… read more here.

Keywords: detection; thrombin detection; low concentration; polypyrrole palladium ... See more keywords
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Synthesis and biocompatibility of an argatroban-modified polysulfone membrane that directly inhibits thrombosis

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recommendations! Published in 2018 at "Journal of Materials Science: Materials in Medicine"

DOI: 10.1007/s10856-018-6054-4

Abstract: AbstractAnticoagulation therapy plays a vital role in the prevention of blood clot formation during hemodialysis and hemofiltration, especially for critical care patients. Here, we synthesized a novel argatroban (Arg)-modified polysulfone (PSf) membrane for anticoagulation. Arg… read more here.

Keywords: psf membrane; modified psf; modified polysulfone; membrane ... See more keywords
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Evaluation of intravenous direct thrombin inhibitor monitoring tests: Correlation with plasma concentrations and clinical outcomes in hospitalized patients

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recommendations! Published in 2019 at "Journal of Thrombosis and Thrombolysis"

DOI: 10.1007/s11239-019-01961-3

Abstract: The parenterally administered direct thrombin inhibitors (DTIs) argatroban and bivalirudin are effective anticoagulants for acute heparin-induced thrombocytopenia (HIT) treatment. The activated partial thromboplastin time (aPTT) has classically been used as the monitoring test to assess… read more here.

Keywords: dtt; discordance; direct thrombin; monitoring ... See more keywords
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Multi-DNAzymes-functionalized gold nanoparticles for ultrasensitive chemiluminescence detection of thrombin on microchip.

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recommendations! Published in 2018 at "Analytica chimica acta"

DOI: 10.1016/j.aca.2018.04.028

Abstract: Herein, a chemiluminescence assay with dual signal amplification has been developed based on multi-DNAzymes-functionalized gold nanoparticles (AuNPs) using in situ rolling circle amplification (RCA) for ultrasensitive detection of thrombin on microchip. In this assay, AuNPs… read more here.

Keywords: detection thrombin; multi; chemiluminescence; multi dnazymes ... See more keywords
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Thrombin lag time is increased in children with mild asthma.

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recommendations! Published in 2019 at "Allergologia et immunopathologia"

DOI: 10.1016/j.aller.2018.07.002

Abstract: BACKGROUND Inflammation and coagulation are closely linked events. Thrombin is the key enzyme in coagulation system and also has roles in inflammation. OBJECTIVE The aim of our study was to evaluate thrombin generation in children… read more here.

Keywords: lag time; mild asthma; time; thrombin lag ... See more keywords