Nets, pulmonary arterial hypertension, and thrombo-inflammation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular medicine"
DOI: 10.1007/s00109-022-02197-0
Abstract: Pulmonary arterial hypertension (PAH) is a progressive and fatal vascular disease in which high blood pressure in the pulmonary artery and remodeling of the pulmonary vasculature ensues. This disorder is characterized by the presence of… read more here.
Keywords: thrombo inflammation; hypertension thrombo; pulmonary arterial; hypertension ... See more keywords
Store-operated calcium entry in thrombosis and thrombo-inflammation.
Sign Up to like & getrecommendations! Published in 2019 at "Cell calcium"
DOI: 10.1016/j.ceca.2018.11.005
Abstract: Cytosolic free calcium (Ca2+) is a second messenger regulating a wide variety of functions in blood cells, including adhesion, activation, proliferation and migration. Store-operated Ca2+ entry (SOCE), triggered by depletion of Ca2+ from the endoplasmic… read more here.
Keywords: store operated; thrombo inflammation; thrombosis thrombo; entry ... See more keywords
Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation
Sign Up to like & getrecommendations! Published in 2021 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2021.103382
Abstract: Background Coagulopathy and inflammation are hallmarks of Coronavirus disease 2019 (COVID-19) and are associated with increased mortality. Clinical and experimental data have revealed a role for neutrophil extracellular traps (NETs) in COVID-19 disease. The mechanisms… read more here.
Keywords: covid associated; fxii activation; thrombo inflammation; activation ... See more keywords
Implication of Platelets in Immuno-Thrombosis and Thrombo-Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.863846
Abstract: In addition to their well-described hemostatic function, platelets are active participants in innate and adaptive immunity. Inflammation and immunity are closely related to changes in platelet reactions and enhanced platelet function in thrombo-inflammation, as well… read more here.
Keywords: thrombosis thrombo; inflammation; thrombo inflammation; platelets immuno ... See more keywords
Platelet in thrombo-inflammation: Unraveling new therapeutic targets
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1039843
Abstract: In the broad range of human diseases, thrombo-inflammation appears as a clinical manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that is recognized as thrombosis and inflammation of superficial veins. However, it… read more here.
Keywords: thrombo inflammation; platelet thrombo; inflammation; role platelets ... See more keywords
Thrombo-Inflammation and Immunological Response in Ischemic Stroke: Focusing on Platelet-Tregs Interaction
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.955385
Abstract: Strokes are mainly caused by thromboembolic obstruction of a major cerebral artery. Major clinical manifestations include paralysis hemiplegia, aphasia, memory, and learning disorders. In the case of ischemic stroke (IS), hyperactive platelets contribute to advancing… read more here.
Keywords: inflammation; thrombo inflammation; platelet; response ... See more keywords