CREM-transgene mice: An animal model of atrial fibrillation and thrombogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis research"
DOI: 10.1016/j.thromres.2017.07.033
Abstract: BACKGROUND The molecular pathomechanisms underlying atrial thrombogenesis are multifactorial and still require detailed investigations. Transgenic mice with cardiomyocyte-directed expression of the transcriptional repressor CREM-IbΔC-X (CREM-TG) represent an experimental model of atrial fibrillation (AF) that shows… read more here.
Keywords: thrombogenesis; model atrial; crem; atrial fibrillation ... See more keywords
DREAM plays an important role in platelet activation and thrombogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2016-07-724419
Abstract: Downstream regulatory element antagonist modulator (DREAM), a transcriptional repressor, is known to modulate pain responses. However, it is unknown whether DREAM is expressed in anucleate platelets and plays a role in thrombogenesis. By using intravital… read more here.
Keywords: dream; thrombogenesis; role; activation ... See more keywords