Thromboinflammation in Brain Ischemia: Recent Updates and Future Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.122.038733
Abstract: Despite decades of promising preclinical validation and clinical translation, ischemic stroke still remains as one of the leading causes of death and disability worldwide. Within its complex pathophysiological signatures, thrombosis and inflammation, that is, thromboinflammation,… read more here.
Keywords: thromboinflammation; thromboinflammation brain; updates future; brain ischemia ... See more keywords
Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc.
Sign Up to like & getrecommendations! Published in 2023 at "EMBO molecular medicine"
DOI: 10.15252/emmm.202216351
Abstract: Thromboinflammation is the major cause of morbidity and mortality in COVID-19 patients, and post-mortem examination demonstrates the presence of platelet-rich thrombi and microangiopathy in visceral organs. Moreover, persistent microclots were detected in both acute COVID-19… read more here.
Keywords: clec2; cov induced; sars cov; net formation ... See more keywords
Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.839632
Abstract: Introduction Air embolism may complicate invasive medical procedures. Bubbles trigger complement C3-mediated cytokine release, coagulation, and platelet activation in vitro in human whole blood. Since these findings have not been verified in vivo, we aimed… read more here.
Keywords: air embolism; complement; air; activation ... See more keywords
Extracellular Vesicles: New Players in the Mechanisms of Sepsis- and COVID-19-Related Thromboinflammation
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24031920
Abstract: Sepsis and COVID-19 patients often manifest an imbalance in inflammation and coagulation, a complex pathological mechanism also named thromboinflammation, which strongly affects patient prognosis. Extracellular vesicles (EVs) are nanoparticles released by cells into extracellular space… read more here.
Keywords: sepsis; extracellular vesicles; sepsis covid; thromboinflammation ... See more keywords
MiR-146a Contributes to Thromboinflammation and Recurrence in Young Patients with Acute Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12071185
Abstract: Studies on older patients have established notable conceptual changes in the etiopathogenesis of acute coronary syndrome (ACS), but little is known about this disease in young patients ( Q2 and T allele) had a two-fold… read more here.
Keywords: cith3 dna; mir 146a; young patients; recurrence ... See more keywords