Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP.
Sign Up to like & getrecommendations! Published in 2022 at "Platelets"
DOI: 10.1080/09537104.2022.2157382
Abstract: Noncoding RNAs (ncRNAs) are a group of RNA molecules that cannot encode proteins, and a better understanding of the complex interaction networks coordinated by ncRNAs will provide a theoretical basis for the development of therapeutics… read more here.
Keywords: thrombopoiesis; rna megakaryocytopoiesis; non coding; roles non ... See more keywords
Application and investigation of thrombopoiesis-stimulating agents in the treatment of thrombocytopenia
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Hematology"
DOI: 10.1177/20406207231152746
Abstract: Platelets, derived from a certain subpopulation of megakaryocytes, are closely related to hemostasis, coagulation, metastasis, inflammation, and cancer progression. Thrombopoiesis is a dynamic process regulated by various signaling pathways in which thrombopoietin (THPO)–MPL is dominant.… read more here.
Keywords: treatment thrombocytopenia; thrombopoiesis stimulating; thrombopoiesis; stimulating agents ... See more keywords
Apoptosis in megakaryocytes: Safeguard and threat for thrombopoiesis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1025945
Abstract: Platelets, generated from precursor megakaryocytes (MKs), are central mediators of hemostasis and thrombosis. The process of thrombopoiesis is extremely complex, regulated by multiple factors, and related to many cellular events including apoptosis. However, the role… read more here.
Keywords: thrombopoiesis; apoptosis; thrombopoiesis apoptosis; apoptosis megakaryocytes ... See more keywords