Scientific premise for the involvement of neutrophil extracellular traps (NETs) in vaccine‐induced thrombotic thrombocytopenia (VITT)
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5covr0621-320rr
Abstract: Following on from the devastating spread of COVID‐19, a major global priority has been the production, procurement, and distribution of effective vaccines to ensure that the global pandemic reaches an end. However, concerns were raised… read more here.
Keywords: induced thrombotic; thrombocytopenia; thrombocytopenia vitt; vitt ... See more keywords
Vaccine‐induced immune thrombotic thrombocytopenia after vaccination against Covid‐19: A clinical dilemma for clinicians and patients
Sign Up to like & getrecommendations! Published in 2021 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2273
Abstract: Summary The coronavirus disease 2019 (Covid‐19) pandemic has had devastating effects on public health worldwide, but the deployment of vaccines for Covid‐19 protection has helped control the spread of SARS Coronavirus 2 (SARS‐CoV‐2) infection where… read more here.
Keywords: immune thrombotic; covid; induced immune; vaccine induced ... See more keywords
Early Outcomes of Bivalirudin Therapy for Thrombotic Thrombocytopenia and Cerebral Venous Sinus Thrombosis After Ad26.COV2.S Vaccination
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Emergency Medicine"
DOI: 10.1016/j.annemergmed.2021.04.035
Abstract: Vaccine-induced thrombotic thrombocytopenia is a newly described disease process in the setting of expanding access to COVID-19 vaccination. The United States Centers for Disease Control and Prevention recommends treatment with an alternative to heparin in… read more here.
Keywords: thrombocytopenia; ad26 cov2; vaccine induced; vaccination ... See more keywords
Cerebral Venous Sinus Thrombosis and Papilledema in Vaccine-Induced Thrombotic Thrombocytopenia After SARS-CoV-2 Vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuro-Ophthalmology"
DOI: 10.1097/wno.0000000000001753
Abstract: A healthy 45-year-old woman received the first dose of AstraZeneca ChAdOx1 vaccination against SARSCoV-2. Eight days later, she presented to the emergency department with new onset of severe bilateral flank pain where she was assessed… read more here.
Keywords: sinus; induced thrombotic; thrombocytopenia; vaccine induced ... See more keywords
Understanding vaccine‐induced thrombotic thrombocytopenia (VITT)
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DOI: 10.1111/imj.15783
Abstract: Vaccine‐induced thrombotic thrombocytopenia (VITT) is a rare, but serious, syndrome characterised by thrombocytopenia, thrombosis, a markedly raised D‐dimer and the presence of anti‐platelet factor‐4 (PF4) antibodies following COVID‐19 adenovirus vector vaccination. VITT occurs at a… read more here.
Keywords: vitt; thrombocytopenia vitt; induced thrombotic; vaccine induced ... See more keywords
Assessment of immunological anti‐platelet factor 4 antibodies for vaccine‐induced thrombotic thrombocytopenia (VITT) in a large Australian cohort: A multicenter study comprising 1284 patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15881
Abstract: Vaccine‐induced thrombotic thrombocytopenia (VITT) is a rare complication of adenovirus‐based vaccines aimed to prevent and minimize COVID‐19 and related pathophysiology. read more here.
Keywords: thrombotic thrombocytopenia; vaccine induced; thrombocytopenia vitt; induced thrombotic ... See more keywords
SARS-CoV-2 Vaccination-Induced Thrombotic Thrombocytopenia: A Rare But Serious Immunologic Complication.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of medicine"
DOI: 10.1146/annurev-med-043021-015237
Abstract: Billions of individuals worldwide have benefited from the unprecedented large-scale rollout of COVID-19 vaccines. Given the sheer number of people that have received these vaccines, it is not surprising that rare side effects are reported… read more here.
Keywords: induced thrombotic; vaccination induced; cov vaccination; thrombotic thrombocytopenia ... See more keywords
Vaccine-induced immune thrombotic thrombocytopenia with atypical vein thrombosis: Implications for clinical practice
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DOI: 10.1177/02683555211068948
Abstract: Objectives Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a new and rare syndrome resulting from the largest vaccination campaign against SARS-CoV-2 in the history of mankind. The aim of this review is to clarify underlying mechanisms,… read more here.
Keywords: immune thrombotic; vaccine induced; treatment; thrombotic thrombocytopenia ... See more keywords
Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know
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DOI: 10.1182/blood.2021012152
Abstract: In this timely Blood Spotlight, Arepally and Ortel discuss the latest information about VITT and highlight key “knowns” as well as pertinent “unknowns.” They also review appropriate treatments for this rare, but important complication of… read more here.
Keywords: immune thrombotic; induced immune; thrombocytopenia know; vaccine induced ... See more keywords
Most anti-PF4 antibodies in vaccine-induced immune thrombotic thrombocytopenia are transient
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2021014214
Abstract: Vaccine-induced Thrombotic Thrombocytopenia (VITT)is triggered by vaccination against COVID-19 with adenovirus vectorvaccines (ChAdOx1 nCoV-19; Ad26.COV2-S). In this observational study, we followed VITT patients for changes in their reactivity ofplatelet-activating anti-platelet factor 4 (PF4) IgG antibodiesby… read more here.
Keywords: vaccine induced; pf4; platelet; thrombotic thrombocytopenia ... See more keywords
Antibody-mediated procoagulant platelets in SARS-CoV-2-vaccination associated immune thrombotic thrombocytopenia
Sign Up to like & getrecommendations! Published in 2021 at "Haematologica"
DOI: 10.3324/haematol.2021.279000
Abstract: The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide. In order to prevent severe infection, mass COVID-19 vaccination campaigns with several vaccine types are currently underway. We report pathological and immunological findings in… read more here.
Keywords: procoagulant platelets; immune thrombotic; antibody mediated; sars cov ... See more keywords