Inhibition of prolyl hydroxylase domain proteins selectively enhances venous thrombus neovascularisation.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis research"
DOI: 10.1016/j.thromres.2018.07.015
Abstract: BACKGROUND Hypoxia within acute venous thrombi is thought to drive resolution through stabilisation of hypoxia inducible factor 1 alpha (HIF1α). Prolyl hydroxylase domain (PHD) isoforms are critical regulators of HIF1α stability. Non-selective inhibition of PHD… read more here.
Keywords: resolution; phd; thrombus resolution; venous thrombus ... See more keywords
Prognostic impact of left ventricular thrombus resolution after myocardial infarction on cardiovascular events and mortality
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.1638
Abstract: Left ventricular thrombus (LVT) is a rare but dreaded complication during the acute phase of acute coronary syndrome (ACS). Incidence rates differ among the observational studies from 1.6% up to 39.0% indicating that many LVT… read more here.
Keywords: resolution; thrombus resolution; impact; mortality ... See more keywords
Impact of left atrial appendage flow velocity on thrombus resolution and clinical outcomes in patients with atrial fibrillation and silent left atrial thrombi: insights from the LAT study
Sign Up to like & getrecommendations! Published in 2024 at "Europace"
DOI: 10.1093/europace/euae120
Abstract: Abstract Aims Blood stasis is crucial in developing left atrial (LA) thrombi. LA appendage peak flow velocity (LAAFV) is a quantitative parameter for estimating thromboembolic risk. However, its impact on LA thrombus resolution and clinical… read more here.
Keywords: left atrial; thrombus resolution; clinical outcomes; thrombi ... See more keywords
Abstract 2094: Sex Differences In Venous Thrombus Resolution In Mice With Metabolic Syndrome
Sign Up to like & getrecommendations! Published in 2024 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvb.44.suppl_1.2094
Abstract: Introduction: Metabolic syndrome (MS) is highly prevalent and have been shown to be associated with mitochondrial impairment and increased cardiovascular and thrombotic risk. It is less understood how MS impacts venous thrombosis and thrombus resolution… read more here.
Keywords: student test; thrombus resolution; mice born; resolution ... See more keywords
Targeting Neutrophil CD14 Inhibits Deep Vein Thrombus Formation and Enhances Thrombus Resolution Following Inferior Vena Cava Stenosis in Mice
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-208713
Abstract: Background: Neutrophil-mediated persistent inflammation and neutrophil extracellular trap formation (NETosis) promote deep vein thrombosis (DVT). CD14, a co-receptor for toll-like receptor 4 (TLR4), is actively synthesized by neutrophils, and the CD14/TLR4 signaling pathway has been… read more here.
Keywords: mice; thrombus resolution; deep vein; stenosis ... See more keywords
Monocyte/macrophage-mediated venous thrombus resolution
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1429523
Abstract: Venous thromboembolism (VTE) poses a notable risk of morbidity and mortality. The natural resolution of the venous thrombus might be a potential alternative treatment strategy for VTE. Monocytes/macrophages merge as pivotal cell types in the… read more here.
Keywords: venous thrombus; monocyte macrophage; thrombus resolution; macrophage mediated ... See more keywords
Shape and Mobility of a Left Ventricular Thrombus Are Predictors of Thrombus Resolution
Sign Up to like & getrecommendations! Published in 2019 at "Korean Circulation Journal"
DOI: 10.4070/kcj.2018.0346
Abstract: Background and Objectives Left ventricular (LV) apical thrombi are usually present with LV dilatation, and oral anticoagulants reduce embolic risk in these patients. However, echocardiographic data regarding thrombus resolution remain limited. We studied its echocardiographic… read more here.
Keywords: mobility; resolution; thrombus resolution; apical thrombi ... See more keywords