High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL
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DOI: 10.1177/2472555218774248
Abstract: Kinase inhibitors have dramatically increased patient survival in a multitude of cancers, including hematological malignancies. However, kinase inhibitors have not yet been integrated into current clinical trials for patients with T-cell-lineage acute lymphoblastic leukemia (T-ALL).… read more here.
Keywords: kinase inhibitors; small molecule; throughput flow; flow cytometry ... See more keywords
High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence
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DOI: 10.3390/ijms21239022
Abstract: Cellular quiescence is a reversible differentiation state when cells are changing the gene expression program to reduce metabolic functions and adapt to a new cellular environment. When fission yeast cells are deprived of nitrogen in… read more here.
Keywords: cytometry combined; quiescence; throughput flow; flow cytometry ... See more keywords