A quantitative, high-throughput method identifies protein–glycan interactions via mass spectrometry
Sign Up to like & getrecommendations! Published in 2019 at "Communications Biology"
DOI: 10.1038/s42003-019-0507-2
Abstract: Glycan binding by glycan-binding proteins and processing by carbohydrate-active enzymes is implicated in physiological and pathophysiological processes. Comprehensive mapping of glycan interactions is essential to understanding of glycan-mediated biology and can guide the development of… read more here.
Keywords: throughput method; quantitative high; biology; high throughput ... See more keywords
Innovative, rapid, high-throughput method for drug repurposing in a pandemic—A case study of SARS-CoV-2 and COVID-19
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DOI: 10.3389/fphar.2023.1130828
Abstract: Several efforts to repurpose drugs for COVID-19 treatment have largely either failed to identify a suitable agent or agents identified did not translate to clinical use; either because of demonstrated lack of clinical efficacy in… read more here.
Keywords: throughput method; rapid high; high throughput; innovative rapid ... See more keywords
High-Throughput Method for the Simultaneous Determination of Doxorubicin Metabolites in Rat Urine after Treatment with Different Drug Nanoformulations
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DOI: 10.3390/molecules27041177
Abstract: Doxorubicin (DOX) is one of the most effective cytotoxic agents against malignant diseases. However, the clinical application of DOX is limited, due to dose-related toxicity. The development of DOX nanoformulations that significantly reduce its toxicity… read more here.
Keywords: dox metabolites; throughput method; treatment different; high throughput ... See more keywords
Rapid, high-throughput method for the quantification of thyroid hormones in rat blood serum using isotope-dilution LC-MS/MS.
Sign Up to like & getrecommendations! Published in 2020 at "Bioanalysis"
DOI: 10.4155/bio-2020-0248
Abstract: Aim: Numerous guideline studies required for regulatory toxicity testing now include the measurement of the thyroid hormones 3,3',5-triiodo-L-thyronine (T3) and L-thyroxine (T4) in blood serum from rodents. A rapid, high-throughput method for the determination of… read more here.
Keywords: throughput method; blood serum; rapid high; thyroid hormones ... See more keywords