High-throughput microfluidic imaging flow cytometry.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2018.08.002
Abstract: Recently, microfluidic-based flow cytometry platforms have been shown to be powerful tools for the manipulation and analysis of single cells and micron-sized particles in flow. That said, current microfluidic flow cytometers are limited in both… read more here.
Keywords: cytometry; imaging flow; flow cytometry; throughput microfluidic ... See more keywords
A high-throughput microfluidic bilayer co-culture platform to study endothelial-pericyte interactions
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-90833-z
Abstract: Microphysiological organ-on-chip models offer the potential to improve the prediction of drug safety and efficacy through recapitulation of human physiological responses. The importance of including multiple cell types within tissue models has been well documented.… read more here.
Keywords: study; platform; culture; throughput microfluidic ... See more keywords
Clog-free high-throughput microfluidic cell isolation with multifunctional microposts
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-94123-6
Abstract: Microfluidics have been applied to filtration of rare tumor cells from the blood as liquid biopsies. Processing is highly limited by low flow rates and device clogging due to a single function of fluidic paths.… read more here.
Keywords: microfluidic cell; clog free; cancer cells; free high ... See more keywords
A high throughput microfluidic system with large ranges of applied pressures for measuring the mechanical properties of single fixed cells and differentiated cells.
Sign Up to like & getrecommendations! Published in 2022 at "Biomicrofluidics"
DOI: 10.1063/5.0085876
Abstract: The mechanical properties of cells are of great significance to their normal physiological activities. The current methods used for the measurement of a cell's mechanical properties have the problems of complicated operation, low throughput, and… read more here.
Keywords: throughput microfluidic; high throughput; mechanical properties; microfluidic system ... See more keywords
Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics
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DOI: 10.1126/science.abf8761
Abstract: Go big or you'll get lost Rational mutagenesis is a common approach to investigating or engineering enzyme function in vitro, but the ease with which one can manipulate protein sequences belies many pitfalls in connecting… read more here.
Keywords: enzyme; site; function; throughput microfluidic ... See more keywords