High-throughput prediction of protein conformational distributions with subsampled AlphaFold2
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DOI: 10.1038/s41467-024-46715-9
Abstract: This paper presents an innovative approach for predicting the relative populations of protein conformations using AlphaFold 2, an AI-powered method that has revolutionized biology by enabling the accurate prediction of protein structures. While AlphaFold 2… read more here.
Keywords: high throughput; relative populations; prediction protein; prediction ... See more keywords
PROSPERous: high-throughput prediction of substrate cleavage sites for 90 proteases with improved accuracy
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DOI: 10.1093/bioinformatics/btx670
Abstract: Summary Proteases are enzymes that specifically cleave the peptide backbone of their target proteins. As an important type of irreversible post-translational modification, protein cleavage underlies many key physiological processes. When dysregulated, proteases' actions are associated… read more here.
Keywords: cleavage; throughput prediction; cleavage sites; substrate ... See more keywords
Evaluation of Throughput Prediction for Adaptive Bitrate Control Using Trace-Based Emulation
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DOI: 10.1109/access.2019.2909399
Abstract: Dynamic adaptive video streaming over HTTP (DASH) is widely studied and has been adopted in modern video players to ensure user quality of experience (QoE). In DASH, adaptive bitrate control is a key part whose… read more here.
Keywords: bitrate control; prediction; adaptive bitrate; throughput prediction ... See more keywords