Genome-Wide High-Throughput RNAi Screening for Identification of Genes Involved in Protein Production.
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DOI: 10.1007/978-1-4939-8730-6_14
Abstract: With an increasing number of blockbuster drugs being recombinant mammalian proteins, protein production platforms that focus on mammalian proteins have had a profound impact in many areas of basic and applied research. Many groups, both… read more here.
Keywords: genes involved; production; protein production; throughput rnai ... See more keywords
Integrative High-Throughput RNAi Screening Identifies BRSK1, STK32C and STK40 as Novel Activators of YAP/TAZ
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DOI: 10.3390/ijms26167810
Abstract: Disruption of the Hippo pathway leads to activation of the YAP/TAZ transcriptional program which promotes tumor initiation, progression and metastasis in diverse cancers. Aggressive triple-negative breast cancers (TNBC) lack an effective therapy; thus, inactivating YAP… read more here.
Keywords: high throughput; brsk1 stk32c; stk40; yap taz ... See more keywords