Droplet‐Microarray: Miniaturized Platform for High‐Throughput Screening of Antimicrobial Compounds
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Biosystems"
DOI: 10.1002/adbi.202000073
Abstract: Currently, there are no time‐saving and cost‐effective high‐throughput screening methods for the evaluation of bacterial drug‐resistance. In this study, a droplet microarray (DMA) system is established as a miniaturized platform for high‐throughput screening of antibacterial… read more here.
Keywords: platform high; miniaturized platform; high throughput; droplet microarray ... See more keywords
High-Throughput Screening and Hierarchical Topography-Mediated Neural Differentiation of Mesenchymal Stem Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202000117
Abstract: Biophysical factors such as anisotropic topography composed of micro/nanosized structures are important for directing the fate of human bone marrow-derived mesenchymal stem cells (hBM-MSCs) and have been applied to neuronal differentiation. Via high-throughput screening (HTS)… read more here.
Keywords: topography; throughput screening; differentiation; mesenchymal stem ... See more keywords
Advancing a rapid, high throughput screening platform for optimization of lentivirus production
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Journal"
DOI: 10.1002/biot.202000621
Abstract: Lentiviral vectors (LVVs) hold great promise as delivery tools for gene therapy and chimeric antigen receptor T cell (CAR‐T) therapy. Their ability to target difficult to transfect cells and deliver genetic payloads that integrate into… read more here.
Keywords: production; rapid high; high throughput; advancing rapid ... See more keywords
High‐Throughput Screening of Signal Peptide Library with Novel Fluorescent Probe
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202100523
Abstract: Nitrile hydratase (NHase) is an excellent biocatalyst for the synthesis of amide compounds and is composed of two heterologous subunits. However, the secretory expression of NHase has been difficult to achieve because of its complex… read more here.
Keywords: peptide library; fluorescent probe; throughput screening; high throughput ... See more keywords
Identification of Compounds That Interfere with High‐Throughput Screening Assay Technologies
Sign Up to like & getrecommendations! Published in 2019 at "Chemmedchem"
DOI: 10.1002/cmdc.201900395
Abstract: A significant challenge in high‐throughput screening (HTS) campaigns is the identification of assay technology interference compounds. A Compound Interfering with an Assay Technology (CIAT) gives false readouts in many assays. CIATs are often considered viable… read more here.
Keywords: identification compounds; high throughput; compounds interfere; assay technologies ... See more keywords
Development of a fast CE method for high throughput screening of ecto‐5′‐nucleotidase inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201800105
Abstract: Overexpression of ecto‐5′‐nucleotidase is found to be linked to cancer progression and other diseases which makes screening of its inhibitors on demand. Unfortunately, there is scarcity of reported ecto‐5′‐nucleotidase inhibitors because of unavailability of simple,… read more here.
Keywords: nucleotidase inhibitors; ecto nucleotidase; high throughput; screening ecto ... See more keywords
Investigation of Photocatalyst Composites for Pollutant Degradation in a Microslit Reactor Utilizing High Throughput Screening Techniques
Sign Up to like & getrecommendations! Published in 2022 at "ChemistryOpen"
DOI: 10.1002/open.202200180
Abstract: Abstract The high‐throughput screening investigations on TiO2 based photocatalyst composites presented here have been carried out in a 60‐fold parallel photoreactor. Additional catalyst testing was performed in a microslit reactor system with immobilized catalysts. For… read more here.
Keywords: microslit reactor; photocatalyst composites; high throughput; throughput screening ... See more keywords
High-throughput Screening for Prescribing Cascades among Real World Statin Initiators.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacoepidemiology and drug safety"
DOI: 10.1002/pds.5607
Abstract: Statins are among the most prevalent medications prescribed and associated with adverse events that may prompt additional treatment (i.e., a prescribing cascade). No comprehensive assessment of statin‐related prescribing cascades has been performed to our knowledge. read more here.
Keywords: cascades among; throughput screening; statin; high throughput ... See more keywords
The Galapagos Chip Platform for High-Throughput Screening of Cell Adhesive Chemical Micropatterns.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202105704
Abstract: In vivo cells reside in a complex extracellular matrix (ECM) that presents spatially distributed biochemical and -physical cues at the nano- to micrometer scales. Chemical micropatterning is successfully used to generate adhesive islands to control… read more here.
Keywords: cell; galapagos chip; throughput screening; high throughput ... See more keywords
High-Throughput Screening to Identify Inhibitors of SSB-Protein Interactions.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1290-3_7
Abstract: The bacterial single-stranded DNA-binding protein (SSB) uses an acidic C-terminal tail to interact with over a dozen proteins, acting as a genome maintenance hub. These SSB-protein interactions are essential, as mutations to the C-terminal tail… read more here.
Keywords: protein interactions; inhibitors ssb; high throughput; identify inhibitors ... See more keywords
High-Throughput Screening Assays to Identify Plant Natural Products with Antifungal Properties Against Fusarium oxysporum.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1795-3_14
Abstract: Fusarium oxysporum is a cross-kingdom fungal pathogen that not only causes devastating plant vascular diseases but can also opportunistically infect humans. Here we describe two high-throughput screening assays, a resazurin cell viability assay and an… read more here.
Keywords: fusarium oxysporum; plant; screening assays; high throughput ... See more keywords