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   Articles with "tht" as a keyword



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An Aggregate Weight-Normalized Thioflavin-T Measurement Scale for Characterizing Polymorphic Amyloids and Assembly Intermediates.

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recommendations! Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7811-3_6

Abstract: The red shift in the fluorescence excitation spectra of thioflavin dyes upon binding to fibrils has been a boon to the amyloid field, offering simple and effective methods for the qualitative detection of amyloid in… read more here.

Keywords: fluorescence; time; tht; tht fluorescence ... See more keywords
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Photophysics of Thioflavin T in deep eutectic solvents

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recommendations! Published in 2018 at "Journal of Luminescence"

DOI: 10.1016/j.jlumin.2018.02.055

Abstract: Abstract Thioflavin-T (ThT) belongs to important biologically active fluorescent sensor for amyloid fibrils. ThT molecule has been extensively applied as a leading sensor for the detection analysis of different type of diseases such as neurodegenerative… read more here.

Keywords: molecule; tht; photophysics thioflavin; deep eutectic ... See more keywords
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Residue-specific binding mechanisms of Thioflavin T to a surface of flat β-sheets within a peptide self-assembly mimic.

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recommendations! Published in 2020 at "Biochemistry"

DOI: 10.1021/acs.biochem.0c00280

Abstract: Thioflavin T (ThT) is a popular fluorescent dye for detecting amyloid, a protein aggregate with a β-sheet-rich structure that causes many neurodegenerative diseases. Despite the dye's popularity, a detailed understanding of its molecular binding mechanism… read more here.

Keywords: specific binding; binding mechanisms; binding mechanism; tht ... See more keywords
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[Cu(C6Cl2F3)(tht)]4: An Extremely Efficient Catalyst for the Aryl Scrambling between Palladium Complexes

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recommendations! Published in 2019 at "Organometallics"

DOI: 10.1021/acs.organomet.8b00885

Abstract: The copper compound [Cu(C6Cl2F3)(tht)]4 (1) (tht: tetrahydrothiophene) is an excellent catalyst for the trans-to-cis isomerization of complexes [PdAr2(tht)2](Ar: fluoroaryl) and also for the exchange of aryls between those palladium complexes. Herein, we also communicate the… read more here.

Keywords: c6cl2f3 tht; catalyst; tht extremely; palladium complexes ... See more keywords
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Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0187294

Abstract: Busulphan (Bu) is an alkylating agent used in the conditioning regimen prior to hematopoietic stem cell transplantation (HSCT). Bu is extensively metabolized in the liver via conjugations with glutathione to form the intermediate metabolite (sulfonium… read more here.

Keywords: containing monooxygenase; metabolic pathway; flavin containing; tht ... See more keywords