Role of thymus in health and disease.
Sign Up to like & getrecommendations! Published in 2022 at "International reviews of immunology"
DOI: 10.1080/08830185.2022.2064461
Abstract: The thymus is a primary lymphoid organ, essential for the development of T-cells that will protect from invading pathogens, immune disorders, and cancer. The thymus decreases in size and cellularity with age referred to as… read more here.
Keywords: thymic involution; cell; thymus health; involution ... See more keywords
A Proposed Link Between Acute Thymic Involution and Late Adverse Effects of Chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.933547
Abstract: Epidemiologic data suggest that cancer survivors tend to develop a protuberant number of adverse late effects, including second primary malignancies (SPM), as a result of cytotoxic chemotherapy. Besides the genotoxic potential of these drugs that… read more here.
Keywords: cell; thymic involution; chemotherapy; tumor ... See more keywords
Transcriptome analysis reveals a potential regulatory mechanism of the lnc-5423.6/IGFBP5 axis in the early stages of mouse thymic involution
Sign Up to like & getrecommendations! Published in 2023 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2023042
Abstract: Age-related thymic involution is one of the significant reasons for induced immunity decline. Recent evidence has indicated that lncRNAs are widely involved in regulating organ development. However, the lncRNA expression profiles in mouse thymic involution… read more here.
Keywords: lnc 5423; thymic involution; mouse thymic; involution ... See more keywords