Polymorphisms in the canine IL7R 3′UTR are associated with thymic output in Labrador retriever dogs and influence post‐transcriptional regulation by microRNA 185
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.12.008
Abstract: &NA; Interleukin‐7 (IL‐7) and its receptor (IL‐7R) are essential for T cell development in the thymus, and changes in the IL‐7/IL‐7R pathway have been implicated in age‐associated thymic involution which results in a reduction of… read more here.
Keywords: thymic output; seed; output; il7r utr ... See more keywords
Dynamic of plasma IL-22 level is an indicator of thymic output after allogeneic hematopoietic cell transplantation.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118849
Abstract: AIMS Interleukin-22 (IL-22) promotes thymus recovery and improves T-cell recovery in preclinical allogeneic hematopoietic cell transplant models. However, the correlation between IL-22 and thymus recovery is unknown in human transplant. MATERIALS AND METHODS In this… read more here.
Keywords: recovery; thymic output; level; plasma level ... See more keywords
Age‐related effects on thymic output and homeostatic T cell expansion following depletional induction in renal transplant recipients
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DOI: 10.1111/ajt.16625
Abstract: Thymic output and homeostatic mature cell proliferation both influence T cell repopulation following depletional induction, though the relative contribution of each and their association with recipient age have not been well studied. We investigated the… read more here.
Keywords: thymic output; age; induction; posttransplantation ... See more keywords
Assessment of Thymic Output Dynamics After in utero Infection of Mice With Coxsackievirus B4
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00481
Abstract: The thymus is the main organ of the lymphatic system, in which T cells undergo a rigorous selection to ensure that their receptors (TCRs) will be functional and will not react against the self. Genes… read more here.
Keywords: thymic output; infection; utero infection; thymus ... See more keywords
Restored Thymic Output after Androgen Blockade Participates in Antitumor Immunity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of immunology"
DOI: 10.4049/jimmunol.2200696
Abstract: The thymus is a hormone-sensitive organ, which involutes with age in response to production of sex steroids. Thymic involution leads to a decrease in the generation of recent thymic emigrants (RTEs), resulting in a reduced… read more here.
Keywords: thymic regeneration; restored thymic; output; response ... See more keywords