LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2074105
Abstract: ABSTRACT Within the thymus, thymic epithelial cells (TECs) provide dedicated thymic stroma microenvironments for T cell development. Because TEC functionality is sensitive to aging and cytoablative therapies, unraveling the molecular elements that coordinate their thymopoietic… read more here.
Keywords: cell; thymic stroma; cd4; development ... See more keywords
Bone Marrow-Derived Cells Contribute to the Maintenance of Thymic Stroma including TECs
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/6061746
Abstract: In paradox to critical functions for T-cell selection and self-tolerance, the thymus undergoes profound age-associated atrophy and loss of T-cell function, further enhanced by cancer therapies. Identifying thymic epithelial progenitor populations capable of forming functional… read more here.
Keywords: thymic stroma; bone marrow; epcam; cd45 epcam ... See more keywords