Thymic stromal lymphopoietin is expressed in human corneal stromal cells and secreted upon protease‐activated receptor 1 activation
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1644
Abstract: Thymic stromal lymphopoietin (TSLP) is an interleukin‐7 (IL‐7) like cytokine that triggers inflammatory responses through activating dendritic cell. It is demonstrated to be involved in a number of disorders, including cancer, gastrointestinal diseases, and autoimmune… read more here.
Keywords: corneal; protease; thymic stromal; stromal cells ... See more keywords
Vitamin B1 Supports the Differentiation of T Cells through TGF-β Superfamily Production in Thymic Stromal Cells
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DOI: 10.1016/j.isci.2020.101426
Abstract: Summary Homeostatic generation of T cells, which occurs in the thymus, is controlled at least in part by endogenous cytokines and ligands. In addition, nutritional factors are other key regulators for the homeostasis of host… read more here.
Keywords: differentiation cells; tgf superfamily; thymic stromal; production ... See more keywords
Interleukin-33 and thymic stromal lymphopoietin, but not interleukin-25, are crucial for development of airway eosinophilia induced by chitin
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DOI: 10.1038/s41598-021-85277-4
Abstract: Exposure to various antigens derived from house dust mites (HDM) is considered to be a risk factor for development of certain allergic diseases such as atopic asthma, atopic dermatitis, rhinitis and conjunctivitis. Chitin is an… read more here.
Keywords: thymic stromal; stromal lymphopoietin; interleukin thymic; airway eosinophilia ... See more keywords
Thymic stromal lymphopoietin drives the development of IL-13+ Th2 cells
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1714348115
Abstract: Significance T helper 2 (Th2) cells are defined by their ability to produce the hallmark cytokine IL-4. However, to mediate allergic inflammation in tissues, Th2 cells must secrete additional cytokines including IL-13 and IL-5. We… read more here.
Keywords: th2 cells; cd4 cells; thymic stromal; stromal lymphopoietin ... See more keywords
Redox status regulates autophagy in thymic stromal cells and promotes T cell tolerance
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2204296119
Abstract: Significance Thymic stromal cells impose T cell self-tolerance by presenting self-antigens to developing T cells and inducing apoptosis in strongly self-reactive cells, a process known as clonal deletion. Self-antigen presentation is facilitated by particularly high… read more here.
Keywords: cells promotes; autophagy thymic; tolerance; thymic stromal ... See more keywords
Thymic stromal lymphopoietin contribution to the recruitment of circulating fibrocytes to the lung in a mouse model of chronic allergic asthma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Asthma"
DOI: 10.1080/02770903.2017.1386213
Abstract: ABSTRACT Objective: Fibrocyte localization to the airways and thymic stromal lymphopoietin (TSLP) overexpression in the lung are features of severe asthma. The aim of this study was to determine whether TSLP contributes to fibrocyte trafficking… read more here.
Keywords: thymic stromal; stromal lymphopoietin; asthma; mouse model ... See more keywords
Thymic Stromal Lymphopoietin-Related Allergic Pathway in Patients With Vernal Keratoconjunctivitis
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DOI: 10.1097/ico.0000000000001832
Abstract: Purpose: To investigate the expression of thymic stromal lymphopoietin (TSLP) and the relevant signaling pathways in the giant papillae obtained from patients with vernal keratoconjunctivitis (VKC) and to study the potential functional role and molecular… read more here.
Keywords: expression; giant papillae; vkc; stromal lymphopoietin ... See more keywords
Correlation of the surface expression of thymic stromal lymphopoietin receptor with the presence of CRLF2 gene rearrangements in children with B‐lineage acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.14028
Abstract: In this study, we aimed to compare the immunophenotype of tumor cells in children with B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL) harboring rearrangements of the CRLF2 gene with that in children without such aberrations with… read more here.
Keywords: lymphoblastic leukemia; thymic stromal; stromal lymphopoietin; acute lymphoblastic ... See more keywords
Plasma thymic stromal lymphopoietin (TSLP) in adults with non-severe asthma: the EGEA study
Sign Up to like & getrecommendations! Published in 2022 at "Thorax"
DOI: 10.1136/thorax-2022-219192
Abstract: Thymic stromal lymphopoietin (TSLP), a cytokine involved in severe asthma treatment, was never studied in non-severe asthma. Among 969 adults from a large epidemiological study, cross-sectional analyses showed that plasma TSLP levels were associated with… read more here.
Keywords: tslp; asthma; non severe; thymic stromal ... See more keywords
Expression of Thymic Stromal Lymphopoietin in Immune-Related Dermatoses
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DOI: 10.1155/2022/9242383
Abstract: Thymic stromal lymphopoietin (TSLP), long known to be involved in Th2 response, is also implicated in multiple inflammatory dermatoses and cancers. The purpose of this study was to improve our understanding of the expression of… read more here.
Keywords: tslp; immune related; related dermatoses; stromal lymphopoietin ... See more keywords
CBX4 Regulates Long-Form Thymic Stromal Lymphopoietin-Mediated Airway Inflammation Through SUMOylation in HDM-Induced Asthma.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2021-0301oc
Abstract: Thymic stromal lymphopoietin (TSLP) presents in two distinct isoforms: short-form (sfTSLP) and long-form (lfTSLP). lfTSLP promotes inflammation while sfTSLP inhibits inflammation in allergic asthma. However, little is known about the regulation of lfTSLP and sfTSLP… read more here.
Keywords: inflammation; sumoylation; stromal lymphopoietin; cbx4 ... See more keywords