MR imaging of thymomas: a combined radiomics nomogram to predict histologic subtypes
Sign Up to like & getrecommendations! Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-07074-3
Abstract: Objectives Accurately predicting the WHO classification of thymomas is urgently needed to optimize individualized therapeutic strategies. We aimed to develop and validate a combined radiomics nomogram for personalized prediction of histologic subtypes in patients with… read more here.
Keywords: radiomics signature; radiomics nomogram; clinical conventional; histologic subtypes ... See more keywords
PD-L1 immuno-expression assay in thymomas: Study of 84 cases and review of literature.
Sign Up to like & getrecommendations! Published in 2018 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2018.03.012
Abstract: BACKGROUND AND AIMS Programmed death ligand 1 (PD-L1), an immune check point inhibitor, is known to be expressed in several malignancies and is being considered as a prognostic factor and a potential immunotherapeutic target. The… read more here.
Keywords: literature; study; expression; expression assay ... See more keywords
Primary mediastinal neoplasms: a report of 1,005 cases from a single institution.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2019.05.42
Abstract: Background This study was an epidemiological analysis of all primary mediastinal neoplasms (PMNs) diagnosed between 2000 and 2016 at the National Tuberculosis and Lung Diseases Research Institute, Poland. Methods All patients with any mediastinal abnormality… read more here.
Keywords: mediastinal neoplasms; primary mediastinal; lymphomas; thymomas ... See more keywords
Application of a combined radiomics nomogram based on CE-CT in the preoperative prediction of thymomas risk categorization
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.944005
Abstract: Objective This study aimed to establish a combined radiomics nomogram to preoperatively predict the risk categorization of thymomas by using contrast-enhanced computed tomography (CE-CT) images. Materials and Methods The clinical, pathological, and CT data of… read more here.
Keywords: thymomas; radiomics nomogram; combined radiomics; risk ... See more keywords
Primary Driver Mutations in GTF2I Specific to the Development of Thymomas
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12082032
Abstract: Thymomas are rare mediastinal tumors that are difficult to treat and pose a major public health concern. Identifying mutations in target genes is vital for the development of novel therapeutic strategies. Type A thymomas possess… read more here.
Keywords: mutations gtf2i; type thymomas; mutant gtf2i; gtf2i ... See more keywords
Metabolic Profiling of Thymic Epithelial Tumors Hints to a Strong Warburg Effect, Glutaminolysis and Precarious Redox Homeostasis as Potential Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14061564
Abstract: Simple Summary Thymomas and thymic carcinomas (TCs) are malignant thymic epithelial tumors (TETs) with poor outcome, if non-resectable. Metabolic signatures of TETs have not yet been studied and may offer new therapeutic options. This is… read more here.
Keywords: metabolite based; thymomas; thymic epithelial; spectroscopy ... See more keywords
ED-B-Containing Isoform of Fibronectin in Tumor Microenvironment of Thymomas: A Target for a Theragnostic Approach
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14112592
Abstract: Simple Summary The extra-domain B fibronectin (ED-B FN) is highly expressed in thymic epithelial tumors (TETs), as demonstrated by in vivo targeting using 131I-labeled L19 small immunoprotein (131I-L19-SIP) and immunohistochemistry with a predominant expression by… read more here.
Keywords: thymomas; microenvironment; stromal cells; expression ... See more keywords