Retracing the evolutionary emergence of thymopoiesis
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abd9585
Abstract: Evolutionary changes in the lymphopoietic capacity of the thymus are recapitulated in mice. The onset of lymphocyte development in the vertebrate primordial thymus, about 500 million years ago, represents one of the foundational events of… read more here.
Keywords: evolutionary emergence; thymopoiesis; thymus; retracing evolutionary ... See more keywords
Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus
Sign Up to like & getrecommendations! Published in 2018 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aao2966
Abstract: Aging, sex, and genetics substantially affect human thymic function. Mining the Milieu Intérieur Personalized medicine partly depends on understanding what causes variance even outside the context of overt disease. The Milieu Intérieur Consortium enrolled 1000… read more here.
Keywords: medicine; int rieur; thymopoiesis; milieu int ... See more keywords