Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia.
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DOI: 10.1172/jci.insight.98699
Abstract: In cystic fibrosis (CF), deletion of phenylalanine 508 (F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel causes misfolding and premature degradation. Considering the numerous effects of the F508del mutation on the assembly… read more here.
Keywords: cftr; cystic fibrosis; f508del cftr; thymosin correct ... See more keywords