The medulla controls effector primed γδT-Cell developmenti in the adult mouse thymus.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202350388
Abstract: γδT cells are produced in the thymus throughout life and provide immunity at epithelial‐rich sites. Unlike conventional αβT cells, γδT‐cell development involves intrathymic acquisition of effector function, with priming for either IL17 or IFN‐γ production… read more here.
Keywords: cell; thymus; ifn; effector ... See more keywords
The Thymus in Experimental Mammary Carcinogenesis and Polychemotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3644-y
Abstract: Histological study of structural transformations in the thymus of Wistar females in induced carcinogenesis (N-methyl-N-nitrosourea injection in the right 2-nd mamma) and polychemotherapy (6 months after tumor growth initiation; cyclophosphamide, methotrexate, and 5-fluorouracyl) was carried… read more here.
Keywords: experimental mammary; tissue; thymus; mammary carcinogenesis ... See more keywords
T cell-depleted cultured pediatric thymus tissue as a model for some aspects of human age-related thymus involution.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-020-00301-1
Abstract: Human age-related thymus involution is characterized by loss of developing thymocytes and the thymic epithelial network that supports them, with replacement by adipose tissue. The mechanisms that drive these changes are difficult to study in… read more here.
Keywords: age related; human age; thymus involution; thymus ... See more keywords
Study of the adoptive immunotherapy on rheumatoid arthritis with Thymus-derived invariant natural killer T cells.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.040
Abstract: BACKGROUND The therapeutic effect of adoptive infusion of specific thymus-derived invariant natural killer T (iNKT) cells in a mouse model of rheumatoid arthritis (RA) was observed, and the mechanism of cellular immunotherapy was preliminarily explored.… read more here.
Keywords: invariant natural; natural killer; thymus; thymus derived ... See more keywords
Detailed theoretical DFT computation/molecular simulation and electrochemical explorations of Thymus vulgaris leave extract for effective mild-steel corrosion retardation in HCl solution
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.115897
Abstract: Abstract Due to the toxic nature of chromatic and phosphatic-based inhibitors, green/non-hazardous inhibitor synthesis has become an interesting topic for researchers in recent days. In the present work, the Thymus vulgaris leaves aqueous extract inhibitory… read more here.
Keywords: surface; vulgaris leave; vulgaris leaves; thymus ... See more keywords
Measurement of fat fraction in the human thymus by localized NMR and three-point Dixon MRI techniques.
Sign Up to like & getrecommendations! Published in 2018 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2018.03.016
Abstract: PURPOSE To develop a protocol to non-invasively measure and map fat fraction, fat/(fat+water), as a function of age in the adult thymus for future studies monitoring the effects of interventions aimed at promoting thymic rejuvenation… read more here.
Keywords: point dixon; fat fraction; mri; thymus ... See more keywords
Essential oils, chemical constituents, antioxidant, antibacterial and in vitro cytotoxic activity of different Thymus species and Zataria multiflora collected from Iran
Sign Up to like & getrecommendations! Published in 2020 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2019.12.005
Abstract: Abstract The present study evaluated the essential oil (EO) compositions, total phenolics (TPC), total flavonoids (TFD), total flavonols (TFL), anthocyanin (Ant) and biological activities of three Thymus population (T. daenensis Celak; T. vulgaris L. and… read more here.
Keywords: zataria multiflora; activity; thymus; chemical constituents ... See more keywords
Antenatal corticosteroid administration is associated with decreased growth of the fetal thymus: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Perinatology"
DOI: 10.1038/s41372-019-0554-z
Abstract: ObjectiveTo examine the effect of antenatal corticosteroid administration (ACS) on fetal thymus growth in women who received ACS compared with gestational-age-matched controls.Study designFetal thymus size and growth were measured in women at risk for preterm… read more here.
Keywords: corticosteroid administration; thymus; antenatal corticosteroid; fetal thymus ... See more keywords
Arsenic exposure impels CD4 commitment in thymus and suppress T cell cytokine secretion by increasing regulatory T cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-07271-z
Abstract: Arsenic is globally infamous for inducing immunosuppression associated with prevalence of opportunistic infection in exposed population, although the mechanism remains elusive. In this study, we investigate the effect of arsenic exposure on thymocyte lineage commitment… read more here.
Keywords: treg cells; cytokine secretion; exposure; regulatory cells ... See more keywords
Radiation inducible MafB gene is required for thymic regeneration
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89836-7
Abstract: The thymus facilitates mature T cell production by providing a suitable stromal microenvironment. This microenvironment is impaired by radiation and aging which lead to immune system disturbances known as thymic involution. Young adult thymus shows… read more here.
Keywords: mafb; thymus; thymic regeneration; radiation inducible ... See more keywords
Impact of CAR T cell therapy on thymus size in children and young adults with acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-12630-2
Abstract: Chimeric Antigen Receptor (CAR) T-cell therapy has demonstrated efficacy in children and young adult patients with acute lymphoblastic leukemia (ALL). The purpose of our study was to investigate thymus size changes after CAR T-cell therapy,… read more here.
Keywords: car; thymus; car cell; cell therapy ... See more keywords