Thyroglobulin determination on silane-antibody functionalized interdigitated dielectrode surface to diagnose thyroid tumour.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2116
Abstract: Thyroid cancer appears in endocrine glands and specific to thyroid glands, has been reported widely. This work was targeted to identify and quantify thyroglobulin by using anti-thyroglobulin antibody complexed silane surface on Interdigitated electrode (IDE)… read more here.
Keywords: determination silane; surface; antibody; thyroglobulin determination ... See more keywords
Multi‐center evaluation of the highly sensitive Abbott ARCHITECT and Alinity thyroglobulin chemiluminescent microparticle immunoassay
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24595
Abstract: Thyroglobulin (Tg) is an essential part for the management of patients with differentiated thyroid carcinoma (DTC) after thyroidectomy. Highly sensitive Tg assays are now established in clinical practice as they facilitate follow‐up of DTC patients.… read more here.
Keywords: alinity; sensitive abbott; center evaluation; highly sensitive ... See more keywords
Reliable neck sonography of nodal thyroglobulin to diagnose recurrent/persistent disease from papillary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23456
Abstract: This study evaluates the correlation between the sonographic features and the nodal fine‐needle aspiration thyroglobulin (FNA‐Tg) in papillary thyroid carcinoma (PTC) patients with the recurrent/persistent lymph node for the purpose of the reasonable selection of… read more here.
Keywords: recurrent persistent; thyroglobulin; thyroid carcinoma; papillary thyroid ... See more keywords
High thyroglobulin and negative whole-body scan: no long-term benefit of empiric radioiodine therapy
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine"
DOI: 10.1007/s12020-021-02647-8
Abstract: Around 10–27% of patients will present elevated thyroglobulin (Tg) levels and negative diagnostic whole-body scan (dxWBS) during differentiated thyroid cancer (DTC) follow-up. Empiric radioactive iodine (RAI) therapy in this context is controversial due to the… read more here.
Keywords: long term; body scan; therapy; whole body ... See more keywords
Clinical use of thyroglobulin: not only thyroid cancer
Sign Up to like & getrecommendations! Published in 2024 at "Endocrine"
DOI: 10.1007/s12020-023-03658-3
Abstract: Thyroglobulin (TG) is a dimeric glycoprotein produced exclusively by mature thyroid tissue and stored within the follicular lumen. It is essential for the organification of iodine and the production of thyroid hormones. The concentration of… read more here.
Keywords: thyroid cancer; thyroglobulin; thyroid; clinical use ... See more keywords
Selection and characterization of an ssDNA aptamer against thyroglobulin.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2020.121690
Abstract: Thyroglobulin (Tg) is a significant biomarker for the diagnose and postoperative monitoring of differentiated thyroid cancer, and its recognition is urgent due to the rising prevalence. In this study, an ssDNA aptamer against Tg was… read more here.
Keywords: aptamer; selection characterization; affinity; thyroglobulin ... See more keywords
Follow-up of differentiated thyroid cancer – what should (and what should not) be done
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-018-0068-3
Abstract: The treatment paradigm for thyroid cancer has shifted from a one-size-fits-all approach to more personalized protocols that range from active surveillance to total thyroidectomy followed by radioiodine remnant ablation. Accurate surveillance tools are available, but… read more here.
Keywords: risk; surveillance; treatment; cancer ... See more keywords
The structure of human thyroglobulin
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-1995-4
Abstract: Thyroglobulin (TG) is the protein precursor of thyroid hormones, which are essential for growth, development and the control of metabolism in vertebrates 1 , 2 . Hormone synthesis from TG occurs in the thyroid gland… read more here.
Keywords: microscopy; human thyroglobulin; thyroid hormones; structure ... See more keywords
Effect of biotin on currently used Beckman thyroglobulin assay and newly reformulated thyroglobulin assay not affected by biotin.
Sign Up to like & getrecommendations! Published in 2024 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqae048
Abstract: OBJECTIVES Biotin causes negative interference with thyroglobulin measurement using the Access thyroglobulin assay. Recently, Beckman reformulated the thyroglobulin assay to overcome biotin interference. We investigated the effect of biotin on both current and newly formulated… read more here.
Keywords: biotin; effect biotin; reformulated thyroglobulin; thyroglobulin ... See more keywords
A-104 Study of the matrix effect for thyroglobulin and calcitonin in fine-needle aspiration of cervical nodules
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Chemistry"
DOI: 10.1093/clinchem/hvae106.103
Abstract: Analysis of material from fine needle aspiration of cervical thyroglobulin nodules with Beckman Coulter reagents on the ACCESS equipment and Calcitonin using the Siemens reagent on the Immulite equipment. The matrix effect, linearity and the… read more here.
Keywords: material; thyroglobulin; study; calcitonin ... See more keywords
B-167 Quantification of Thyroglobulin in Serum for Clinical Research using SISCAPA Workflow Combined with LC-MS/MS
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Chemistry"
DOI: 10.1093/clinchem/hvae106.527
Abstract: Accurate measurement of Thyroglobulin (Tg) using existing immunoassay-based techniques can be challenging in the presence of anti-Tg antibodies (TgAb), which can prevent the binding of Tg to assay antibodies thus leading to non-quantifiable Tg concentrations.… read more here.
Keywords: using siscapa; method; workflow combined; clinical research ... See more keywords