Thyroglobulin determination on silane-antibody functionalized interdigitated dielectrode surface to diagnose thyroid tumour.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2116
Abstract: Thyroid cancer appears in endocrine glands and specific to thyroid glands, has been reported widely. This work was targeted to identify and quantify thyroglobulin by using anti-thyroglobulin antibody complexed silane surface on Interdigitated electrode (IDE)… read more here.
Keywords: determination silane; surface; antibody; thyroglobulin determination ... See more keywords
Multi‐center evaluation of the highly sensitive Abbott ARCHITECT and Alinity thyroglobulin chemiluminescent microparticle immunoassay
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24595
Abstract: Thyroglobulin (Tg) is an essential part for the management of patients with differentiated thyroid carcinoma (DTC) after thyroidectomy. Highly sensitive Tg assays are now established in clinical practice as they facilitate follow‐up of DTC patients.… read more here.
Keywords: alinity; sensitive abbott; center evaluation; highly sensitive ... See more keywords
Reliable neck sonography of nodal thyroglobulin to diagnose recurrent/persistent disease from papillary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23456
Abstract: This study evaluates the correlation between the sonographic features and the nodal fine‐needle aspiration thyroglobulin (FNA‐Tg) in papillary thyroid carcinoma (PTC) patients with the recurrent/persistent lymph node for the purpose of the reasonable selection of… read more here.
Keywords: recurrent persistent; thyroglobulin; thyroid carcinoma; papillary thyroid ... See more keywords
High thyroglobulin and negative whole-body scan: no long-term benefit of empiric radioiodine therapy
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine"
DOI: 10.1007/s12020-021-02647-8
Abstract: Around 10–27% of patients will present elevated thyroglobulin (Tg) levels and negative diagnostic whole-body scan (dxWBS) during differentiated thyroid cancer (DTC) follow-up. Empiric radioactive iodine (RAI) therapy in this context is controversial due to the… read more here.
Keywords: long term; body scan; therapy; whole body ... See more keywords
Selection and characterization of an ssDNA aptamer against thyroglobulin.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2020.121690
Abstract: Thyroglobulin (Tg) is a significant biomarker for the diagnose and postoperative monitoring of differentiated thyroid cancer, and its recognition is urgent due to the rising prevalence. In this study, an ssDNA aptamer against Tg was… read more here.
Keywords: aptamer; selection characterization; affinity; thyroglobulin ... See more keywords
Follow-up of differentiated thyroid cancer – what should (and what should not) be done
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-018-0068-3
Abstract: The treatment paradigm for thyroid cancer has shifted from a one-size-fits-all approach to more personalized protocols that range from active surveillance to total thyroidectomy followed by radioiodine remnant ablation. Accurate surveillance tools are available, but… read more here.
Keywords: risk; surveillance; treatment; cancer ... See more keywords
The structure of human thyroglobulin
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-1995-4
Abstract: Thyroglobulin (TG) is the protein precursor of thyroid hormones, which are essential for growth, development and the control of metabolism in vertebrates 1 , 2 . Hormone synthesis from TG occurs in the thyroid gland… read more here.
Keywords: microscopy; human thyroglobulin; thyroid hormones; structure ... See more keywords
Thyroglobulin assay in fluids from lymph node fine needle-aspiration washout: influence of pre-analytical conditions.
Sign Up to like & getrecommendations! Published in 2017 at "Annales de biologie clinique"
DOI: 10.1684/abc.2017.1225
Abstract: The aim of this study was to evaluate the pre-analytical factors contributing to uncertainty in thyroglobulin measurement in fluids from fine-needle aspiration (FNA) washout of cervical lymph nodes. We studied pre-analytical stability, in different conditions,… read more here.
Keywords: storage; fna washout; pre analytical; needle aspiration ... See more keywords
Preoperative Serum Thyroglobulin and Its Correlation with the Burden and Extent of Differentiated Thyroid Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12030625
Abstract: Lymph node metastasis (LNM) in differentiated thyroid cancer (DTC) is usually detected with preoperative ultrasonography; however, this has limited sensitivity for small metastases, and there is currently no predictive biomarker that can help to inform… read more here.
Keywords: extent; preoperative serum; serum thyroglobulin; burden extent ... See more keywords
The Prognostic Role of Postablative Non-Stimulated Thyroglobulin in Differentiated Thyroid Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13020310
Abstract: Simple Summary In the management of patients with differentiated thyroid cancer, thyroglobulin (Tg) is used as a tumor marker to predict residual disease. After surgery, the presence or absence of persistent disease and the risk… read more here.
Keywords: risk; differentiated thyroid; disease; non stimulated ... See more keywords
Genome-Wide Association Analysis and Genomic Prediction of Thyroglobulin Plasma Levels
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042173
Abstract: Thyroglobulin (Tg) is an iodoglycoprotein produced by thyroid follicular cells which acts as an essential substrate for thyroid hormone synthesis. To date, only one genome-wide association study (GWAS) of plasma Tg levels has been performed… read more here.
Keywords: genome wide; thyroglobulin; wide association; plasma levels ... See more keywords