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   Articles with "thyroid" as a keyword



Diagnostic Accuracy of Fine-Needle Biopsy in the Detection of Thyroid Malignancy: A Systematic Review and Meta-analysis.

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recommendations! Published in 2022 at "JAMA surgery"

DOI: 10.1001/jamasurg.2022.4989

Abstract: Importance Fine-needle biopsy (FNB) became a critical part of thyroid nodule evaluation in the 1970s. It is not clear how diagnostic accuracy of FNB has changed over time. Objective To conduct a systematic review and… read more here.

Keywords: time; thyroid; accuracy; malignancy ... See more keywords

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer.

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recommendations! Published in 2025 at "FEBS letters"

DOI: 10.1002/1873-3468.70207

Abstract: Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy characterized by dedifferentiation and radioiodine refractoriness. We investigated whether EZH2-mediated H3K27me3 deposition represses thyroid differentiation genes (TDGs) in ATC cells. Online ChIP-seq analyses and CUT&RUN confirmed… read more here.

Keywords: iodide uptake; anaplastic thyroid; thyroid cancer; cell ... See more keywords

Stratification of follicular thyroid tumours using data‐independent acquisition proteomics and a comprehensive thyroid tissue spectral library

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recommendations! Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13198

Abstract: Thyroid nodules occur in about 60% of the population. A major challenge in thyroid nodule diagnosis is to distinguish between follicular adenoma (FA) and carcinoma (FTC). Here, we present a comprehensive thyroid spectral library covering… read more here.

Keywords: thyroid; comprehensive thyroid; thyroid tumours; follicular thyroid ... See more keywords

Modeling Human Thyroid Development by Fetal Tissue‐Derived Organoid Culture

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202105568

Abstract: Abstract Euthyroidism is of profound importance for lifetime health. However, the early diagnosis or therapeutics of thyroid developmental defects has not been established, mainly due to limited understanding of human thyroid development and a lack… read more here.

Keywords: culture; fetal thyroid; thyroid development; thyroid ... See more keywords

Neonatal thyroid hormone levels in association with autism spectrum disorder

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recommendations! Published in 2017 at "Autism Research"

DOI: 10.1002/aur.1708

Abstract: Thyroid hormones (TH) are critical in early neurodevelopment, but few studies have examined whether neonatal TH levels influence risk of autism spectrum disorder (ASD). This study linked California neonatal screening data with live birth and… read more here.

Keywords: autism; thyroid; spectrum disorder; autism spectrum ... See more keywords

Causal relationship between insomnia and thyroid disease: A bidirectional Mendelian randomization study

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recommendations! Published in 2024 at "Brain and Behavior"

DOI: 10.1002/brb3.70046

Abstract: Some correlations between thyroid disorders and insomnia have been found in previous studies; however, the causal relationship between them is unclear. The aim of this study was to investigate the causal relationship between insomnia and… read more here.

Keywords: relationship insomnia; relationship; causal relationship; thyroid ... See more keywords

Ancillary molecular testing of indeterminate thyroid nodules

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recommendations! Published in 2018 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22012

Abstract: Cytological specimens from thyroid nodules are increasingly being adopted as the first available material for cost effectively managing patients in the era of personalized medicine. Cytology aspirates not only play a central role in providing… read more here.

Keywords: thyroid nodules; indeterminate thyroid; molecular testing; ancillary molecular ... See more keywords
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Can ultrasound systems for risk stratification of thyroid nodules identify follicular carcinoma?

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recommendations! Published in 2020 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22235

Abstract: Ultrasound (US) risk stratification systems (RSSs) have been developed to reduce the number of unnecessary fine needle aspirations (FNAs) of thyroid nodules. These systems were designed primarily to identify papillary thyroid carcinomas, thus their performance… read more here.

Keywords: thyroid nodules; risk stratification; carcinoma; thyroid ... See more keywords
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Thyroid paraganglioma: A diagnostic pitfall in thyroid FNA

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recommendations! Published in 2020 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22390

Abstract: Thyroid paragangliomas are extremely rare and often are misdiagnosed by preoperative fine‐needle aspiration (FNA) because their cytologic features overlap with those of other thyroid neoplasms. The objective of this study was to review the cytomorphology… read more here.

Keywords: fna; thyroid paraganglioma; diagnostic pitfall; pitfall thyroid ... See more keywords

Development and validation of an RNA sequencing–based classifier for medullary thyroid carcinoma on thyroid FNA

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recommendations! Published in 2022 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22643

Abstract: Medullary thyroid carcinoma (MTC) is an uncommon malignancy of C- cell origin that accounts for < 3% of all thyroid cancers. 1,2 However, the prognosis for MTC, which is derived from parafollicular C cells, has… read more here.

Keywords: thyroid carcinoma; mtc; thyroid; validation ... See more keywords

Risk stratification of cytologically indeterminate thyroid nodules with nondiagnostic or benign cytology on repeat FNA: Implications for molecular testing and surveillance

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recommendations! Published in 2023 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22684

Abstract: Evidence guiding the management of cytologically indeterminate thyroid nodules with nondiagnostic (ND) or benign cytology on repeat fine‐needle aspiration (FNA) is limited. This study evaluates the utility of molecular testing and estimates the risk of… read more here.

Keywords: thyroid nodules; cytologically indeterminate; thyroid; nodules nondiagnostic ... See more keywords