Differentiation between thyroid‐associated orbitopathy and Graves’ disease by iTRAQ‐based quantitative proteomic analysis
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13172
Abstract: Graves’ ophthalmopathy, also known as thyroid‐associated orbitopathy (TAO), is the most common inflammatory eye disease in adults. The most common etiology for TAO is Graves’ disease (GD); however, proteomic research focusing on differences between GD… read more here.
Keywords: tao; thyroid associated; associated orbitopathy; differentiation ... See more keywords
Prediction of treatment response to intravenous glucocorticoid in patients with thyroid-associated ophthalmopathy using T2 mapping and T2 IDEAL.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2021.109839
Abstract: PURPOSE To investigate the performance of combined T2 mapping and T2 iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) in orbital tissues to predict the therapeutic efficacy of intravenous glucocorticoids… read more here.
Keywords: eom wfmax; thyroid associated; eom; treatment response ... See more keywords
Novel role of SF1 in alleviating thyroid-associated ophthalmopathy through the AMPK/mTOR signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.11.097
Abstract: BACKGROUND/AIM Thyroid-associated ophthalmopathy (TAO) is a chronic autoimmune disorder characterized by an increased volume of adipose/connective tissue. This study aims to explore whether steroidogenic factor 1 (SF1) is implicated in development of TAO through the… read more here.
Keywords: thyroid associated; mtor signaling; signaling pathway; ampk ... See more keywords
Elevated IL-38 inhibits IL-23R expression and IL-17A production in thyroid-associated ophthalmopathy.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107300
Abstract: IL-23/IL-23R and PGE2/EP2+EP4 have been recognized as crucial signals that promote Th17 differentiation in many autoimmune diseases, including thyroid-associated ophthalmopathy (TAO). However, the interactive role of IL-23R in IL-23/Th17 signaling and PGE2/Th17 signaling has not… read more here.
Keywords: 23r 17a; tao; thyroid associated; pge2 ... See more keywords
Thyroid-associated orbitopathy and tears: A proteomics study.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2017.09.001
Abstract: To date, Thyroid-Associated Orbitopathy (TAO), an autoimmune inflammatory disease affecting the eye, remains poorly characterised and its diagnosis challenging. The aim of this study was to investigate the tears of the TAO patients in order… read more here.
Keywords: thyroid associated; associated orbitopathy; disease; tao patients ... See more keywords
The involvement of T cell pathogenesis in thyroid-associated ophthalmopathy
Sign Up to like & getrecommendations! Published in 2018 at "Eye"
DOI: 10.1038/s41433-018-0279-9
Abstract: Thyroid-associated ophthalmoapthy (TAO) is the most common orbital disease. As an autoimmune disorder, it is caused by self-reactive lymphocytes that escape immune tolerance, but the mechanism is not fully understood. The basic process of TAO… read more here.
Keywords: tao; thyroid associated; involvement cell; pathogenesis ... See more keywords
Machine learning unveils hypoxia-immune gene hub for clinical stratification of thyroid-associated ophthalmopathy
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-05107-9
Abstract: Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder affecting the orbit, potentially resulting in blindness. This study focused on the role of hypoxia in its pathogenesis through integrative bioinformatics and experimental validation. Five differentially expressed genes… read more here.
Keywords: tao; hypoxia; machine learning; associated ophthalmopathy ... See more keywords
Bulbar Conjunctival Microvascular Alterations in Thyroid-Associated Ophthalmopathy Patients with Different Activities
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DOI: 10.1080/02713683.2020.1849729
Abstract: ABSTRACT Purpose: To evaluate the morphologic and hemodynamic changes of bulbar conjunctival vessels in thyroid-associated ophthalmopathy (TAO) patients and the correlations with the activity. Methods: Patients diagnosed as TAO with different clinical activity scores (CAS)… read more here.
Keywords: blood flow; tao; thyroid associated; associated ophthalmopathy ... See more keywords
The Role of TPOAb in Thyroid-Associated Orbitopathy: A Systematic Review.
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DOI: 10.1080/09273948.2021.1942498
Abstract: Introduction: Thyroid-associated orbitopathy (TAO) is one of the most common autoimmune inflammatory disorders of the orbit. The presence of anti-thyroid antibodies is believed to play a role in the pathogenesis and clinical status of the… read more here.
Keywords: tao; thyroid associated; associated orbitopathy; tpoab ... See more keywords
Thyroid-associated orbitopathy in patients with thyroid carcinoma
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DOI: 10.1097/md.0000000000008768
Abstract: Rationale: Thyroid-associated orbitopathy (TAO) is most often seen in patients with autoimmune thyroid disease. Data about TAO occurred in patients with thyroid carcinoma are rare. We give a report of 5 patients to present the… read more here.
Keywords: tao; thyroid associated; patients thyroid; thyroid carcinoma ... See more keywords
Alterations in dynamic regional homogeneity within default mode network in patients with thyroid-associated ophthalmopathy
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DOI: 10.1097/wnr.0000000000002056
Abstract: Thyroid-associated ophthalmopathy (TAO) is a significant autoimmune eye disease known for causing exophthalmos and substantial optic nerve damage. Prior investigations have solely focused on static functional MRI (fMRI) scans of the brain in TAO patients,… read more here.
Keywords: brain; tao; healthy controls; dreho ... See more keywords