Evaluation of Medical Surveillance and Incidence of Post-September 11, 2001, Thyroid Cancer in World Trade Center-Exposed Firefighters and Emergency Medical Service Workers.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2020.0950
Abstract: Importance Elevated incidence rates of thyroid cancer among World Trade Center (WTC)-exposed individuals may be associated with the identification of asymptomatic cancers during medical surveillance. Objective To examine the association between WTC exposure and thyroid… read more here.
Keywords: incidence; fire department; epidemiology; thyroid cancer ... See more keywords
Patient Preference in Physician Decision-Making for Patients With Low- to Intermediate-Risk Differentiated Thyroid Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA surgery"
DOI: 10.1001/jamasurg.2023.0359
Abstract: This survey study describes the association between patient preference and physician decision-making in thyroid cancer. read more here.
Keywords: patient preference; physician decision; thyroid cancer; decision making ... See more keywords
Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer.
Sign Up to like & getrecommendations! Published in 2025 at "FEBS letters"
DOI: 10.1002/1873-3468.70207
Abstract: Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy characterized by dedifferentiation and radioiodine refractoriness. We investigated whether EZH2-mediated H3K27me3 deposition represses thyroid differentiation genes (TDGs) in ATC cells. Online ChIP-seq analyses and CUT&RUN confirmed… read more here.
Keywords: iodide uptake; anaplastic thyroid; thyroid cancer; cell ... See more keywords
CRISPR‐mediated knockout of VEGFR2/KDR inhibits cell growth in a squamous thyroid cancer cell line
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13399
Abstract: Squamous and anaplastic thyroid cancers are the most aggressive and life‐threatening cancer types in humans, with the involvement of lymph nodes in 59% of cases and distant metastases in 26% of cases of all thyroid… read more here.
Keywords: cell; kdr; squamous thyroid; thyroid cancer ... See more keywords
Amorphous A-BiOI@PEG Nanoenzyme Targets Imaging and Synergistic Phototherapy in Differentiated Thyroid Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202514116
Abstract: The integration of medical nanomaterials into cancer diagnosis and treatment presents a multifaceted challenge, given the simultaneous necessity of achieving high targeting and excellent diagnostic and therapeutic efficacy. Herein, a PEGylated amorphous BiOI (a-BiOI@PEG) nanoenzyme… read more here.
Keywords: cancer; peg nanoenzyme; bioi peg; thyroid cancer ... See more keywords
Lipid‐Peptide‐mRNA Nanoparticles Augment Radioiodine Uptake in Anaplastic Thyroid Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204334
Abstract: Restoring sodium iodide symporter (NIS) expression and function remains a major challenge for radioiodine therapy in anaplastic thyroid cancer (ATC). For more efficient delivery of messenger RNA (mRNA) to manipulate protein expression, a lipid‐peptide‐mRNA (LPm)… read more here.
Keywords: mrna; peptide; thyroid cancer; lipid peptide ... See more keywords
Dynamics of The Γδtcr Repertoires During The Dedifferentiation Process and Pilot Implications for Immunotherapy of Thyroid Cancer
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202306364
Abstract: γδ T cells are evolutionarily conserved T lymphocytes that manifest unique antitumor efficacy independent of tumor mutation burden (TMB) and conventional human leukocyte antigen (HLA) recognition. However, the dynamic changes in their T cell receptor… read more here.
Keywords: cancer; repertoires dedifferentiation; tcr repertoires; thyroid cancer ... See more keywords
Spatial and Single‐Cell Transcriptomics Unraveled Spatial Evolution of Papillary Thyroid Cancer
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DOI: 10.1002/advs.202404491
Abstract: Recurrence and metastasis are the major issues for papillary thyroid cancer (PTC). Current morphological and molecular classification systems are not satisfied for PTC diagnosis due to lacking variant‐specific morphological criteria and high signal‐to‐noise in mutation‐based… read more here.
Keywords: evolution; single cell; spatial single; thyroid cancer ... See more keywords
Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed-Type Thyroid Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202507602
Abstract: Despite WWOX's established role as a tumor suppressor, conclusive evidence linking germline WWOX loss‐of‐function variants to oncogenesis remains scarce. Two germline homozygous WWOX missense variants (p.P252A and p.P282A) are identified in a patient with histological… read more here.
Keywords: cancer; mixed type; histological mixed; thyroid cancer ... See more keywords
Surgeon volume and prognosis of patients with advanced papillary thyroid cancer and lateral nodal metastasis
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10655
Abstract: Surgery is the most important treatment modality for papillary thyroid cancer (PTC). However, the relationship between surgeon volume and long‐term oncological outcomes has not been explored. read more here.
Keywords: papillary thyroid; surgeon volume; thyroid cancer;
Time to calcitonin normalization after surgery for node‐negative and node‐positive medullary thyroid cancer
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Surgery"
DOI: 10.1002/bjs.11071
Abstract: It remains unclear when postoperative serum calcitonin levels should be measured in patients with medullary thyroid cancer (MTC) and, specifically, whether this decision should be based on the preoperative calcitonin level or nodal status. read more here.
Keywords: medullary thyroid; surgery; time calcitonin; thyroid cancer ... See more keywords