Using Ion Torrent sequencing to study genetic mutation profiles of fatal thyroid cancers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2017.05.007
Abstract: BACKGROUND/PURPOSE Surgery followed by radioiodine is a mainstay of treatment for thyroid cancers of follicular origins. However, about 5% of the thyroid cancers are non-operable and/or radioiodine-refractory diseases, which are either locally advanced or metastatic… read more here.
Keywords: mutation; fatal thyroid; thyroid cancers; ion torrent ... See more keywords
Emerging roles of circular RNAs in regulating the hallmarks of thyroid cancer
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DOI: 10.1038/s41417-024-00736-0
Abstract: Thyroid cancer is a prevalent endocrine malignancy with increasing incidence in recent years. Although most thyroid cancers grow slowly, they can become refractory, leading to a high mortality rate once they exhibit recurrence, metastasis, resistance… read more here.
Keywords: cancer; roles circular; thyroid cancers; thyroid cancer ... See more keywords
Global research trends on systemic lupus erythematosus and thyroid cancers (1964–2023): A scientometric and visualized study
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DOI: 10.1097/md.0000000000038511
Abstract: Over the past 3 decades numerous studies have reported an association between systemic lupus erythematosus (SLE) and thyroid cancers. However, there has been no scientometric analysis in this area of research. To perform a comprehensive… read more here.
Keywords: thyroid cancers; systemic lupus; 1964 2023; research ... See more keywords
Abstract CT011: Efficacy and safety of selpercatinib in RET fusion-positive cancers other than lung or thyroid cancers
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DOI: 10.1158/1538-7445.am2021-ct011
Abstract: Introduction: Selpercatinib, a first-in-class highly selective and potent RET kinase inhibitor, is approved in multiple countries for the treatment of RET fusion-positive lung or thyroid cancers. RET fusions are also implicated in the pathogenesis of… read more here.
Keywords: fusion positive; thyroid cancers; non; ret fusion ... See more keywords
Cardiac Metastasis from Medullary Thyroid Cancers with Long-Term Survival under Vandetanib
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DOI: 10.1159/000517716
Abstract: Background: Cardiac metastases from thyroid cancers are uncommon with a poor prognosis. There is a lack of long-term follow-up studies. Cases: We report 2 cases of cardiac metastasis from medullary thyroid cancer (MTC). Both patients… read more here.
Keywords: metastasis; long term; cardiac metastasis; thyroid cancers ... See more keywords
Mutational analysis of radiation-induced subsequent thyroid cancers in pediatric patients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e22531
Abstract: e22531Background: The genetic landscape of radiation induced pediatric thyroid cancers is unclear. Radiation (RT) induced thyroid cancers frequently demonstrate tumorigenesis driven by fusion oncog... read more here.
Keywords: radiation induced; thyroid cancers; mutational analysis; analysis radiation ... See more keywords
Efficacy and safety of selpercatinib in advanced RET-altered thyroid cancers: A meta-analysis and systematic review.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.e18073
Abstract: e18073 Background: Selpercatinib is a highly selective RET inhibitor that is used for the treatment of RET-mutant medullary thyroid cancers, but its efficacy and safety is not fully understood. Our objective is to summarize available… read more here.
Keywords: advanced ret; thyroid cancers; efficacy; ret altered ... See more keywords
7144 Lack of TPO Antibodies Heralds “Immune Escape” of Aggressive Thyroid Cancers of Follicular Origin: An International Retrospective Analysis of 1,943 Consecutive Thyroidectomy Cases
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvae163.2264
Abstract: Abstract Disclosure: R.D. Paparodis: None. E. Karvounis: None. A. Kapezanou: None. D. Bantouna: None. S. Livadas: None. G. Simeakis: None. D.P. Askitis: None. I. Androulakis: None. N.G. Angelopoulos: None. D. Zianni: None. I. Perogamvros: None.… read more here.
Keywords: tpo antibody; thyroid cancers; none; tpo antibodies ... See more keywords
Immune responses in the thyroid cancer microenvironment: making immunotherapy a possible mission.
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DOI: 10.1530/erc-17-0316
Abstract: The incidence of thyroid cancers has been steadily increasing worldwide over the past few decades. Although five-year survival rates for differentiated thyroid cancers are upwards of 90%, clinical outcomes for patients with undifferentiated, recurrent and/or… read more here.
Keywords: immune; thyroid cancer; cancer microenvironment; thyroid cancers ... See more keywords
Redifferentiation of radioiodine-refractory thyroid cancers.
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DOI: 10.1530/erc-19-0491
Abstract: The management of radioiodine refractory thyroid cancers (RAIR TC) is challenging for the clinician. Tyrosine kinase inhibitors classically prescribed in this setting can fail due to primary or acquired resistance or the necessity of drug… read more here.
Keywords: refractory thyroid; radioiodine refractory; thyroid cancers;
Molecular mechanisms of resistance to kinase inhibitors in thyroid cancers.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine-related cancer"
DOI: 10.1530/erc-22-0129
Abstract: Protein kinases play critical roles in cell survival, proliferation and motility. Their dysregulation is therefore a common feature in the pathogenesis of a number of solid tumors, including thyroid cancers. Inhibiting activated protein kinases has… read more here.
Keywords: thyroid cancers; molecular mechanisms; kinase; mechanisms resistance ... See more keywords